Results 221 to 230 of about 71,628 (244)

Identification of Natural and Artificial Modifications in DNA at the Nanometer Level

Journal of Raman Spectroscopy, EarlyView.
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig, Prabha Singh, Miklos Veres, Roman Holomb, Volker Deckert   +4 more
wiley   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

Replication fork stalling in late S-phase elicits nascent strand degradation by DNA mismatch repair. [PDF]

Nucleic Acids Res
Colicino-Murbach E, Hathaway C, Dungrawala H.   +2 more
europepmc   +1 more source

Topological Photonic Devices and Circuits at Terahertz Frequencies

Laser &Photonics Reviews, EarlyView.
This review examines how 3D topological insulators and emerging topological photonic phases enable robust, low‐loss and defect‐immune terahertz devices. Fundamental properties, device implementations and topological transport mechanisms are surveyed, revealing new opportunities for reconfigurable, high‐performance THz components and scalable ...
Samane Kalhor, Srabani Kar, Ranjan Singh, Kaveh Delfanazari   +3 more
wiley   +1 more source

Dissecting DNA-mismatch-repair-driven mutational processes in human cells

Owusu M, Menche J, Loizou J, Weghorn D, Weghorn D.   +4 more
europepmc   +1 more source

Combining single-molecule and structural studies reveals protein and DNA conformations and assemblies that govern DNA mismatch repair. [PDF]

Curr Opin Struct Biol
Erie DA, Weninger KR.
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

DNA mismatch repair deficiency in conjunctival melanoma. [PDF]

Eye (Lond)
Rodriguez A, Moser J, Ramasubramanian A.
europepmc   +1 more source

HMGB1 Assists in Overcoming Cisplatin Resistance in Chemoresistant Human Ovarian Cancer Cells

Molecular Carcinogenesis, EarlyView.
ABSTRACT Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes.
Van Huynh, Guliang Wang, Anirban Mukherjee, Karen M. Vasquez   +3 more
wiley   +1 more source

The ubiquitin ligase UBR4 and the deubiquitylase USP5 modulate the stability of DNA mismatch repair protein MLH1. [PDF]

J Biol Chem
Mao C, Li S, Che J, Liu D, Mao X, Rao H.
europepmc   +1 more source