Results 31 to 40 of about 1,452,122 (130)
DNA supercoiling and transcription in bacteria: a two-way street
BMC Molecular and Cell Biology, 2019 Background The processes of DNA supercoiling and transcription are interdependent because the movement of a transcription elongation complex simultaneously induces under- and overwinding of the DNA duplex and because the initiation, elongation and ...
Charles J. Dorman
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Frontiers in Microbiology, 2023 DNA supercoiling is central to many fundamental processes of living organisms. Its average level along the chromosome and over time reflects the dynamic equilibrium of opposite activities of topoisomerases, which are required to relax mechanical stresses
Ivan Junier +4 more
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Frontiers in Cellular and Infection Microbiology, 2012 The prevalence of fluoroquinolone (FQ)-resistant Campylobacter has become a concern for public health. To facilitate the control of FQ-resistant Campylobacter, it is necessary to understand the impact of FQ resistance on the fitness of Campylobacter in ...
Jing eHan +7 more
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Mechanical Caging of Nucleic Acids Enabled by Light‐Activated Synthetic Molecular Motors
Angewandte Chemie, EarlyView.A synthetic light‐driven molecular motor imposes mechanical constraints on nucleic acids, enabling “mechanical caging” as a new mode to regulate DNA structure and function through mechanical input rather than chemical masking. ABSTRACT Control over nucleic acid activity is central to biotechnology and therapeutic development.
Yuchen Ma +10 more
wiley +2 more sources
Supercoiling Effects on Short-Range DNA Looping in E. coli. [PDF]
PLoS ONE, 2016 DNA-protein loops can be essential for gene regulation. The Escherichia coli lactose (lac) operon is controlled by DNA-protein loops that have been studied for decades.
Lauren S Mogil +2 more
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, 2019 A. A linear double-stranded DNA becomes a topologically constrained molecule if the two ends are covalently joined, forming a circle. Rules of DNA topology are explained using such a molecule (ccc-DNA) in which a numerical parameter called the linking ...
Zhong Qian (8119712) +2 more
core +1 more source
Data in Brief, 2020 In enteric bacteria, DNA supercoiling is highly responsive to environmental conditions. Host specific features of environment serve as cues for the expression of genes required for colonization of host niches via changing supercoiling [1].
Natalia E. Gogoleva +4 more
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Functional Fibers in Soft Robotics: Advances in Material, Structural, and Systemic Tactics
Advanced Robotics Research, EarlyView.Fiber‐form robotic systems offer a scalable pathway toward embodied intelligence in soft robotics. This review surveys functional fibers as material, structural, and systemic elements, highlighting advances in responsive materials, architectural programing, and fabrication strategies.
Joonhee Won +5 more
wiley +1 more source
Nature Communications, 2021 In cells, DNA is arranged into topologically-constrained (supercoiled) structures, but how this supercoiling affects the detailed double-helical structure of DNA remains unclear.
Alice L. B. Pyne +12 more
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Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone
Advanced Science, EarlyView.A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad +12 more
wiley +1 more source