Results 31 to 40 of about 5,202,482 (355)

Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells [PDF]

, 2017
Docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid found in fish oil, is a multi-target agent and exerts anti-inflammatory and anticancer activities alone or in combination with chemotherapies.
D'Eliseo, Donatella, DI RENZO, Livia Maria, Santoni, Angela, Velotti, Francesca   +3 more
core   +1 more source

Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production

Journal of Lipid Research, 1998
The objective of this study was to investigate membrane fatty acids for their effects on mitochondrial function in live cells. Mitochondrial potential and oxidant production were measured in human colonic adenocarcinoma (HT-29) cells with membranes ...
Steven M. Watkins, Lynne C. Carter, J. Bruce German   +2 more
doaj   +1 more source

Omega‐3 Fatty Acids and Heart Rhythm, Rate, and Variability in Atrial Fibrillation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Previous randomized control trials showed mixed results concerning the effect of omega‐3 fatty acids (n‐3 FAs) on atrial fibrillation (AF). The associations of n‐3 FA blood levels with heart rhythm in patients with established AF are unknown ...
Philipp Baumgartner, Martin F. Reiner, Andrea Wiencierz, Michael Coslovsky, Nicole R. Bonetti, Mark G. Filipovic, Stefanie Aeschbacher, Michael Kühne, Christine S. Zuern, Nicolas Rodondi, Jolanda Oberle, Giorgio Moschovitis, Thomas F. Lüscher, Giovanni G. Camici, Stefan Osswald, David Conen, Jürg H. Beer   +16 more
doaj   +1 more source

The Differential Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Cardiometabolic Risk Factors: A Systematic Review

International Journal of Molecular Sciences, 2018
A large body of evidence supports the cardioprotective effects of the long-chain omega-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
Jacqueline K. Innes, P. Calder
semanticscholar   +1 more source

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]

, 2009
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim, Illig, Thomas, Koletzko, Berthold, Lattka, Eva   +3 more
core   +1 more source

Diurnal rhythm of plasma EPA and DHA in healthy adults [PDF]

, 2020
Knowledge of the diurnal variation in circulating omega-3 polyunsaturated fatty acids (n-3 PUFAs) may be an important consideration for the development of dosing protocols designed to optimise tissue delivery of these fatty acids.
Avery, Hannah, Calder, Philip C., Forster, Joanne, Husberg, Cathrine, Hustvedt, Svein-Olaf, Jackson, Philippa, Kennedy, David, Khan, Julie   +7 more
core   +2 more sources

Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat

Journal of Lipid Research, 1993
Dietary triglycerides containing predominantly poly-unsaturated fatty acids (PUFAs) are known to reduce plasma total and low density lipoprotein (LDL) cholesterol concentrations relative to triglycerides containing predominantly saturated fatty acids ...
DK Spady
doaj   +1 more source

Metabolism of n-3 polyunsaturated fatty acids and modification of phospholipids in cultured rabbit aortic smooth muscle cells.

Journal of Lipid Research, 1985
The metabolism of the linolenic acid family (n-3) of fatty acids, e.g., linolenic, eicosapentaenoic, and docosahexaenoic acids, in cultured smooth muscle cells from rabbit aorta was compared to the metabolism of linoleic and arachidonic acids.
N Morisaki, T Kanzaki, Y Fujiyama, I Osawa, K Shirai, N Matsuoka, Y Saito, S Yoshida   +7 more
doaj   +1 more source

Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice

Scientific Reports, 2017
Docosahexaenoic acid (DHA) is uniquely concentrated in the brain, and is essential for its function, but must be mostly acquired from diet. Most of the current supplements of DHA, including fish oil and krill oil, do not significantly increase brain DHA,
D. Sugasini, Riya Thomas, Poorna C. R. Yalagala, Leon M. Tai, P. Subbaiah   +4 more
semanticscholar   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source