Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
ABSTRACT Objective Evaluate the rate and trend of preterm birth (PTB) and the associated perinatal survival in Hong Kong. Design Population‐based, repeated cross‐sectional time series. Setting All public maternity hospitals. Population 845 640 singleton and 26 748 twin deliveries from 2000 to 2023.
Ka Wang Cheung +11 more
wiley +1 more source
Enhancement of docosahexaenoic acid production by overexpression of ATP-citrate lyase and acetyl-CoA carboxylase in Schizochytrium sp. [PDF]
Han Xiao +3 more
openalex +1 more source
Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. [PDF]
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell (HSPC) maintenance.
Han, Tianxu +10 more
core +2 more sources
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma +9 more
wiley +1 more source
Development of omega-3 enriched egg using fish-oil based fowl feed supplement
SUMMARY: Nutritional content of egg can be manipulated by altering hen feed. Developing an economical fowl feed supplement to produce omega-3 enriched egg from purified fish oil, produced using a proprietary method, leads to a value-added product.
Benny Antony +6 more
doaj +1 more source
Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells
Background The transmissible spongiform encephalopathies, otherwise known as prion diseases, occur following the conversion of the cellular prion protein (PrPC) to an alternatively folded, disease-associated isoform (PrPSc).
Salmona Mario +4 more
doaj +1 more source
Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]
Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla +2 more
core +1 more source
Abstract Aims This study investigated the long‐term effects of a multidomain intervention on cognition and metabolic control in patients with type 2 diabetes and mild cognitive impairment (MCI). Materials and methods Outpatients aged 70–85 years were randomized to an 18‐month multidomain intervention (comprising metabolic/vascular risk management ...
Taiki Sugimoto +16 more
wiley +1 more source
Development of Hydrophobically Modified Casein Derivative-Based Delivery System for Docosahexaenoic Acids by an Acid-Induced Gelation. [PDF]
Ha HK, Woo DB, Lee MR, Lee WJ.
europepmc +1 more source

