Results 111 to 120 of about 41,199 (244)

Lipid Dynamics in the Amyloid Cascade Hypothesis: Evaluating the Biological Relevance of In Vitro Models

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle   +6 more
wiley   +1 more source

Cannabigerol Alleviates Obesity‐Induced Mitochondrial Dysfunction by Cardiolipin Fatty Acid Remodeling

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Graphical overview of the effects of the high‐fat, high‐sucrose (HFHS) diet regime and 2‐week cannabigerol (CBG) treatment on the intramuscular long‐chain fatty acids (LCFAs) trafficking and lipid metabolism, with subsequent implications for mitochondrial cardiolipin (CL) composition in the red gastrocnemius muscle.
Patrycja Bielawiec   +3 more
wiley   +1 more source

Association between omega-3 fatty acid intake and ADHD symptoms among early adolescents aged 10–12 years: a cross-sectional study in Palestine

open access: yesInternational Journal of Adolescent Medicine and Health
Deficits in omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been implicated in attention-deficit/hyperactivity disorder (ADHD).
Muhanna Safaa   +3 more
doaj   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Omega-3 fatty acids and chemotherapy-induced toxicities: mechanisms and emerging evidence with a pediatric focus

open access: yesNutrition & Metabolism
Background Omega-3 fatty acids are polyunsaturated fats that are essential for proper cell structure and function. The primary types of omega-3 fatty acids include alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA ...
R. Maldonado-Salinas   +9 more
doaj   +1 more source

Early and Larval Development of the Marine Species Grey Triggerfish (Balistes capriscus, Gmelin, 1789) and the Use of Different Organisms as First Food Sources

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT The aim of this study was to provide an initial description of the embryology and larval development of Balistes capriscus species obtained from natural spawning in captivity. The study also aimed to assess the stocking density and the impact of offering four types of live food as the initial feed during the larviculture phase. Observations of
Henrique David Lavander   +9 more
wiley   +1 more source

Impact of Varying Soybean Oil Concentrations on the Cytokine Profile of Skeletal Muscle and Liver of Pigs: A Systems Biology Approach

open access: yesAnimal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Lipids are important for metabolic processes, mainly cytokine regulation in the skeletal muscle and liver. Considering the soybean oil concentration, a weighted gene co‐expression network analysis (WGCNA) was used to perform an integrative analysis in skeletal muscle and liver tissues.
Fernanda Nery Ciconello   +9 more
wiley   +1 more source

Redirecting Alzheimer's disease therapeutics: Multitarget drugs and complementary non‐pharmacological strategies

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco   +4 more
wiley   +1 more source

Prediction of cognitive outcome and progression to dementia using ω6‐PUFA/ω3‐PUFA ratio

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION The polyunsaturated fatty acids (PUFAs) omega‐6 (ω6) and omega‐3 (ω3) are linked to cognitive performance and Alzheimer's‐type dementia (DAT), but ω3‐PUFA supplementation offers limited benefits. We propose that the ω6‐PUFA/ω3‐PUFA ratio better explains cognitive decline and DAT risk.
Víctor Andrade   +19 more
wiley   +1 more source

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