Results 111 to 120 of about 78,435 (282)

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

Differential effects of EPA vs. DHA on postprandial vascular function and the plasma oxylipin profile in men [PDF]

open access: yes, 2016
Our objective was to investigate the impact of EPA versus DHA, on arterial stiffness and reactivity, and underlying mechanisms (with a focus on plasma oxylipins), in the postprandial state.
Aedin Cassidy   +63 more
core   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

open access: yesPediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang   +6 more
wiley   +1 more source

The fatty acids of Euglena gracilis

open access: yesJournal of Lipid Research, 1964
The complete structures of 51 fatty acids of Euglena gracilis have been determined. These include saturated fatty acids from C9 to C19, monounsaturated fatty acids from C13 to C19, diunsaturated fatty acids from C15 to C20, tri-unsaturated fatty acids ...
Edward D. Korn
doaj   +1 more source

Studies relating to Polyunsaturated Fatty Acid (PUFA) Supplementation and Fertility in Cattle [PDF]

open access: yes, 2007
End of project reportReproductive inefficiency has a significant impact on the economic performance of both dairy and beef herds, particularly in seasonal calving systems. Nutrition plays a fundamental role in reproduction. Furthermore, there is emerging
Childs, Stuart   +3 more
core  

Proteomic and metabolic signatures of female reproductive factors and risk of age‐related ocular diseases: A large prospective cohort study

open access: yesVIEW, EarlyView.
The full editable vector source file of this graphical abstract is uploaded as a supplementary EPS file for typesetting. All elements are copyright‐free. Abstract Age‐related ocular diseases (ARODs), including cataract, primary open‐angle glaucoma (POAG), and age‐related macular degeneration (AMD), are leading causes of vision impairment and exhibit ...
Linge Jian   +6 more
wiley   +1 more source

OMEGA-3 SUPPLEMENTATION ATTENUATES THE PRODUCTION OF C-REACTIVE PROTEIN IN MILITARY PERSONNEL DURING 5 DAYS OF INTENSE PHYSICAL STRESS AND NUTRITIONAL RESTRICTION

open access: yesBiology of Sport, 2012
The effects of omega-3 (n-3) polyunsaturated fatty acid (PUFA) supplementation on the serum concentration of C-reactive protein (CRP) and activity of creatine kinase (CK) were investigated in military personnel. The concentrations of CRP and CK were used
Eduardo Porto Santos   +6 more
doaj  

Failure of a dietary model to affect markers of inflammation in domestic cats [PDF]

open access: yes, 2014
Background: Oxidative stress and inflammation can be altered by dietary factors in various species. However, little data are available in true carnivorous species such as domestic cats.
Cox, Eric   +6 more
core   +2 more sources

Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans

open access: yesIntegrative Zoology, EarlyView.
Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong   +8 more
wiley   +1 more source

Integrative polygenic analysis of the protective effects of fatty acid metabolism on disease as modified by obesity

open access: yesFrontiers in Nutrition
Dysregulation of fatty acid metabolites can play a crucial role in the progression of complex diseases, such as cardiovascular disease, digestive diseases, and metabolic diseases.
Courtney Astore, Greg Gibson
doaj   +1 more source

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