Results 111 to 120 of about 77,870 (288)
Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells
Brain Pathology, EarlyView.Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son +7 more
wiley +1 more source
Frontiers in NutritionDysregulation of fatty acid metabolites can play a crucial role in the progression of complex diseases, such as cardiovascular disease, digestive diseases, and metabolic diseases.
Courtney Astore, Greg Gibson
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma +9 more
wiley +1 more source
Development of omega-3 enriched egg using fish-oil based fowl feed supplement
Journal of Applied Poultry ResearchSUMMARY: Nutritional content of egg can be manipulated by altering hen feed. Developing an economical fowl feed supplement to produce omega-3 enriched egg from purified fish oil, produced using a proprietary method, leads to a value-added product.
Benny Antony +6 more
doaj +1 more source
The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]
, 2014 Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
core
The Fish Behind Fish Feed: Rethinking Transparency Using DNA Tools
Fish and Fisheries, EarlyView.ABSTRACT Aquaculture is now the fastest growing food sector and may be a promising solution to increasing seafood demands. Yet, carnivorous aquaculture species such as salmon and seabass continue to rely on fishmeal and fish oil (FMFO), which are derived largely from pelagic fish that are sometimes key to the food security of some coastal nations. This
Marine Cusa +4 more
wiley +1 more source
Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells
BMC Biology, 2008 Background The transmissible spongiform encephalopathies, otherwise known as prion diseases, occur following the conversion of the cellular prion protein (PrPC) to an alternatively folded, disease-associated isoform (PrPSc).
Salmona Mario +4 more
doaj +1 more source
Development of Hydrophobically Modified Casein Derivative-Based Delivery System for Docosahexaenoic Acids by an Acid-Induced Gelation. [PDF]
Food Sci Anim Resour, 2023 Ha HK, Woo DB, Lee MR, Lee WJ.
europepmc +1 more source
Early onset preeclampsia is characterized by altered placental lipid metabolism and a premature increase in circulating FABP4 [PDF]
, 2010 Preeclampsia is a pregnancy-associated disorder that manifests as a sudden increase in maternal blood pressure accompanied by proteinuria. Because the placenta is a key organ in preeclampsia, we used proteomic and lipidomic analyses to compare placentae ...
Aaron Booy +5 more
core +1 more source
The FEBS Journal, EarlyView.Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump +10 more
wiley +1 more source