Results 11 to 20 of about 254,386 (241)

Method for assigning double-stranded RNA structures

BioTechniques, 2005
Trevor S. Brown, Philip C. Bevilacqua
doaj   +3 more sources

Characteristic of the active substance of the Saccharomyces cerevisiae preparation having radioprotective properties

Вавиловский журнал генетики и селекции, 2020
The paper describes some biological features of the radioprotective effect of double-stranded RNA preparation. It was found that yeast RNA preparation has a prolonged radioprotective effect after irradiation by a lethal dose of 9.4 Gy.
G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov, S. S. Bogachev   +16 more
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Reovirus Low-Density Particles Package Cellular RNA

Viruses, 2021
Packaging of segmented, double-stranded RNA viral genomes requires coordination of viral proteins and RNA segments. For mammalian orthoreovirus (reovirus), evidence suggests either all ten or zero viral RNA segments are simultaneously packaged in a ...
Timothy W. Thoner, Xiang Ye, John Karijolich, Kristen M. Ogden   +3 more
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Performance comparison of four types of target enrichment baits for exome DNA sequencing

Hereditas, 2021
Background Next-generation sequencing technology is developing rapidly and target capture sequencing has become an important technique. Several different platforms for library preparation and target capture with different bait types respectively are ...
Juan Zhou, Mancang Zhang, Xiaoqi Li, Zhuo Wang, Dun Pan, Yongyong Shi   +5 more
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Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis

Communications Biology, 2021
Nakano et al. use high-speed AFM and cryo-EM to study influenza virus RNA synthesis in vitro. They observe the synthesis of two types of RNA: folded single stranded RNA associated to an intact viral ribonucleoprotein (vRNP) and looped, double stranded ...
Masahiro Nakano, Yukihiko Sugita, Noriyuki Kodera, Sho Miyamoto, Yukiko Muramoto, Matthias Wolf, Takeshi Noda   +6 more
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Contribution of Small RNA Pathway to Interactions of Rice with Pathogens and Insect Pests

Rice, 2021
Small RNAs (sRNAs) are mainly classified into microRNAs (miRNAs) and small interfering RNAs (siRNAs) according to their origin. miRNAs originate from single-stranded RNA precursors, whereas siRNAs originate from double-stranded RNA precursors that are ...
Qin Feng, Yan Li, Zhi-Xue Zhao, Wen-Ming Wang   +3 more
doaj   +1 more source

Double Stranded RNA in Human Seminal Plasma

Frontiers in Genetics, 2017
Recently, human semen was shown to contain cell-free nucleic acids, such as DNA, long single stranded RNA, and small RNAs–miRNA and piRNA. The RNAs have been suggested to have potential biological roles as communication molecules between cells and in the
Maxim V. Zagoskin, Maxim V. Zagoskin, Richard E. Davis, Dmitry V. Mukha   +3 more
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UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair

Nature Communications, 2021
R loops are formed when single-stranded RNA anneals to one strand of DNA, forming three-stranded structures containing DNA-RNA hybrids and the displaced non-template single-stranded DNA. Here the authors reveal that the DNA:RNA helicase UPF1 plays a role
Greg H. P. Ngo, Julia W. Grimstead, Duncan M. Baird   +2 more
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In vitro antiviral activity of a double-stranded RNA sodium salt-based medicinal product against SARS-CoV-2

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Innate immune activation in the early phases of COVID-19 infection and subsequent interferon induction may help control viral replication and protect cells not yet infected with SARS-CoV-2.
G. M. Ignatyev, E. Yu. Shustova, E. A. Rogozhina, P. A. Belyi, K. Ya. Zaslavskaya, V. A. Merkulov   +5 more
doaj   +1 more source

Mismatched Double-Stranded RNA [PDF]

Drugs in R & D, 2004
Ampligen [polyI:polyC12U] is a mismatched double-stranded RNA that acts by inducing interferon production (immunomodulator) and by activating an intracellular enzyme (RNase-L) against viral RNA transcripts (antiviral). Ampligen, currently under development by Hemispherx Biopharma in the US, acts on the immunological system through T-lymphocyte ...
openaire   +2 more sources