Results 41 to 50 of about 16,723 (215)
Contribution of DROSHA N-terminus to MicroRNA Biogenesis [PDF]
, 2021 학위논문 (석사) -- 서울대학교 대학원 : 농업생명과학대학 농생명공학부, 2021. 2. 신찬석.MicroRNAs(miRNAs) are small non-coding RNAs of ~22nucleotides (nt) in length , which regulate post-transcription by silencing target gene.
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DataSheet3_Conservation of Differential Animal MicroRNA Processing by Drosha and Dicer.XLSX
, 2022 In complex biochemical systems, an enzyme, protein, or RNA, symbolized as E, has hundreds or thousands of substrates or interacting partners. The relative specificity hypothesis proposes that such an E would differentially interact with and influence its
Fanming Yang (11889628) +6 more
core +1 more source
Endocrine Regulations, 2018 Objectives. It has been shown that dysregulation of miRNAs expression contributes to the pathogenesis and progression of the diabetes and diabetes-related complications. Drosha, DGCR8, Dicer, and Ago-2 are involved in the miRNA maturation. The aim of the
Soufi Farhad Ghadiri +5 more
doaj +1 more source
Cell Reports, 2019 Summary: MicroRNA (miRNA) processing begins with Drosha cleavage, the fidelity of which is critical for downstream processing and mature miRNA target specificity.
Xavier Bofill-De Ros +11 more
doaj +1 more source
Expression of DROSHA and DICER genes in peripheral blood leukocytes in lung sarcoidosis [PDF]
Терапевтический архив, 2018 Aim. To study the expression level of the genes DROSHA and DICER in peripheral blood leukocytes (PBL) of patients with sarcoidosis of the lungs Materials and methods.
I E Malysheva +3 more
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Structures of human Drosha and Giardia Dicer.
, 2019 Front view ribbon representation of the structure of (A) Drosha and (B) Dicer. The proteins are colored with similar colors for similar domains. Domains colors are as follow: N-terminal Platform domain (Drosha: cyan, Dicer: dark blue), putative PAZ-like ...
Rotem Aharoni (8108177) +1 more
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PLoS ONE, 2017 Canonical processing of miRNA begins in the nucleus with the Microprocessor complex, which is minimally composed of the RNase III enzyme Drosha and two copies of its cofactor protein DGCR8.
Joshua C Kranick +3 more
doaj +1 more source
The conserved single-cleavage mechanism of animal DROSHA enzymes
Communications Biology, 2021 Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.
Thuy Linh Nguyen +2 more
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The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source