Results 51 to 60 of about 17,302 (170)
miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.ABSTRACT
Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets Zhen‐Zhen Guo, Ao‐Ying Li, Ting‐Ting Xiang, Zu‐Hao Zhang, Ao Deng, Yang Han +5 morewiley +1 more sourceThe amount of 3’UTR-derived piRNAs does not decrease in follicle cells lacking Drosha activity.
, 2015 Normalized profiles of ovarian piRNAs (sense: up (red); antisense: down (blue)) that map to the traffic jam, jim and GC32000 3'UTRs in tj-GAL4>WT-Drosha* and tj-GAL4>TN-Drosha* libraries (upper panels), in tj-GAL4>WT-Drosha and tj-GAL4>TN-Drosha (middle ...Vincent Serrano (741212), Bruno Mugat (741210), Claudia Armenise (741213), Christine Brun (3176), Abdou Akkouche (741211), Blaise Li (3297861), Alain Pélisson (70071), David Van Vactor (53862), Tudor A. Fulga (53861), Séverine Chambeyron (741214) +9 morecore +1 more sourceThe microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder [PDF]
, 2022 DROSHA encodes a ribonuclease that is a subunit of the Microprocessor complex and is involved in the first step of microRNA (miRNA) biogenesis. To date, DROSHA has not yet been associated with a Mendelian disease.Undiagnosed Diseases Network, Telischi, Fred, Grajewski, Alana, Network, Undiagnosed Diseases, Sacco, Ralph, McCauley, Jacob, Bademci, Guney, Mikati, Mohamad A., Barbouth, Deborah, Bellen, Hugo J., Zuchner, Stephan, Minogue, Amanda L., Liu, Xue, Lam, Byron, Chang, Ta, Wangler, Michael F., Saporta, Mario, Kranz, Peter G., Tekin, Mustafa, Seemann, Jacob H., Carrasquillo, Olveen, Levitt, Roy, Isasi, Rosario, El-Dairi, Mays, Ariani, Francesca, Jasien, Joan, Senturk, Mumine, Arur, Swathi, Fallerini, Chiara, Minogue, Amanda L, Bellen, Hugo J, Yamamoto, Shinya, Wangler, Michael F, Renieri, Alessandra, Harland, Jake, Seemann, Jacob H, Galluzzi, Paolo, Stong, Nicholas, Shashi, Vandana, Mikati, Mohamad A, Lopergolo, Diego, Jiang, Yong-Hui, Schoch, Kelly, Barish, Scott, Kranz, Peter G, Kansagra, Sujay, Mari, Francesca, Dustin Baldridge, Swathi Arur, Elisabeth McGee, Daniel Doherty, Heather A Colley, Lynette Rives, Timothy Schedl, Matthew T Wheeler, Maria T Acosta, Ta Chen Peter Chang, Lindsay C Burrage, Matthew Coggins, Devon Bonner, Donna Novacic, Kelly Hassey, Hongzheng Dai, Avi Nath, Rebecca Signer, Deepak A Rao, Chris A Walsh, Lorraine Potocki, Camilo Toro, Dave Viskochil, Jimann Shin, Peter Byers, Seema R Lalani, Jyoti G Dayal, Euan A Ashley, Lilianna Solnica-Krezel, Mahshid S Azamian, Diane B Zastrow, Gerard T Berry, C Ron Scott, Ronit Marom, David R Adams, Matthew Deardorff, Devin Oglesbee, Gary D Clark, null null, Catherine A Groden, Julian A Martínez-Agosto, Jennefer N Kohler, Alexa T McCray, Andrew B Crouse, Carlos A Bacino, Rebecca C Spillmann, Alana Grajewski, Mariska Davids, Aaron Quinlan, Mumine Senturk, Shirley Nieves-Rodriguez, Nicola Longo, Kathy Sisco, Ashley Andrews, Yong-Hui Jiang, Laurel A Cobban, Sujay Kansagra, Judy Schaechter, Kimberly LeBlanc, Ian R Lanza, Deborah Barbouth, Eva Morava, David B Goldstein, Diego Lopergolo, Bryan Mak, Jason Hom, Jacob McCauley, J Carl Pallais, Jonathan A Bernstein, Lee-kai Wang, Stan F Nelson, Guoyun Yu, Kelly Schoch, Angela Sun, Tyra Estwick, Brendan H Lee, Cynthia M Cooper, Liliana Fernandez, Michael Bamshad, Archana N Raja, Michael Cunningham, Dana Kiley, Cynthia J Tifft, Brenna Boyd, Stephen Pak, Catherine H Sillari, Chiara Fallerini, Wendy Raskind, Sandra K Loo, Christina G S Palmer, Calum A MacRae, Teri A Manolio, Olveen Carrasquillo, Brent L Fogel, Alden Huang, Fariha Jamal, Christine M Eng, Susan L Samson, Mary Koziura, Edwin K Silverman, Richard L Maas, Donna M Krasnewich, Chloe M Reuter, Janet S Sinsheimer, Roy Levitt, Melissa Walker, Lisa T Emrick, Laura Amendola, Elijah Kravets, Emily G Kelley, Allyn McConkie-Rosell, Rena A Godfrey, Francesca Ariani, Yong Huang, May Christine V Malicdan, Brendan C Lanpher, Shruti Marwaha, Eva Baker, Mays El-Dairi, Scott Barish, Colleen E McCormack, Fuki M Hisama, Tiphanie P Vogel, Mohamad A Mikati, Anna Bican, Edward Behrens, Monte Westerfield, Jacinda B Sampson, Amy K Robertson, Chunli Zhao, Suman Jayadev, Laure Fresard, Mark Wener, Queenie K-GTan, David D Draper, Katherine Wesseling Perry, Genecee Renteria, Joan M Stoler, Carlos Ferreira, F Sessions Cole, Jeremy D Woods, Shirley Sutton, Alica M Goldman, Ralph Sacco, Guney Bademci, Jennifer Kennedy, Nicholas Stong, David A Sweetser, Maura Ruzhnikov, Pinar Bayrak-Toydemir, Stephanie Wallace, Emilie D Douine, C Christopher Lau, Richard A Lewis, Ashok Balasubramanyam, Jacob H Seemann, Virginia Sybert, Edward C Smith, Christina Lam, Xue Zhong Liu, Jordan Whitlock, Mercedes E Alejandro, Heather Mefford, Willa Thorson, Shinya Yamamoto, Andrea L Gropman, Ingrid A Holm, Barbara N Pusey, Marta M Majcherska, Kathleen Sullivan, Mario Saporta, Joseph Loscalzo, John Yang, David J Eckstein, Pankaj B Agrawal, Paul G Fisher, Paolo M Moretti, Jake Harland, Hsiao-Tuan Chao, Naghmeh Dorrani, Alyssa A Tran, Jill A Rosenfeld, John A Phillips III, Rizwan Hamid, Alan H Beggs, Matt Velinder, Stephan Zuchner, Nicholas StongJ, Nicole M Walley, Hugo J Bellen, Anne Hing, Daniel Wegner, Jimmy Bennet, Michael F Wangler, Francesca Mari, Vandana Shashi, Katrina Dipple, Emily Solem, Sarah K Nicholas, Natalie Rosenwasser, Paolo Galluzzi, Manish J Butte, Cecelia P Tamburro, Laura Duncan, Jijun Wan, Ghayda Mirzaa, Justin Alvey, Mariko Nakano-Okuno, Gabrielle Brown, William E Byrd, Elizabeth L Fieg, Laurie C Findley, Martha Horike-Pyne, Thomas C Markello, Elly Brokamp, Susan Korrick, John J Mulvihill, Jim Bale, Matthew Might, Lefkothea Karaviti, Byron Lam, Colleen E Wahl, Lorenzo Botto, William A GahlIan-Glass, Laura A Mamounas, Fred Telischi, Dawn Earl, Cecilia Esteves, Kevin S Smith, Anita Beck, Elizabeth Blue, Beth A Martin, Valerie V Maduro, Precilla D'Souza, Martin G Martin, Tara Wenger, Ellen F Macnamara, Rong Mao, Joy D Cogan, Sharyn A Lincoln, Margaret Adam, Carsten Bonnenmann, Laura Pace, Neil A Hanchard, Prashant Sharma, Terra R Coakley, Beverly Berg-Rood, Marni Falk, Lynne A Wolfe, Gill Bejerano, Lance H Rodan, Neil H Parker, Peter G Kranz, Stephanie Bivona, James P Orengo, John Bohnsack, Deborah Krakow, Jennifer Wambach, Hane Lee, Alessandra Renieri, Katie Golden-Grant, ennifer A Sullivan, Mustafa Tekin, Sirisak Chanprasert, Jean M Johnston, Jennifer E Posey, Deborah Nickerson, Marie Morimoto, Jeanette C Papp, Gail P Jarvik, David R Murdock, Daryl A Scott, Shweta U Dhar, Pengfei Liu, Irma Gutierrez, Tiina K Urv, Patricia A Ward, Heidi Cope, Adeline Vanderver, Rosario Isasi, Joan Jasien, Kenneth Maravilla, Elizabeth A Burke, Sihoun Hahn, Jeffrey Jarvik, J Lawrence Merritt, Holly K Tabor, Surendra Dasari, Irman Forghani, William J Craigen, Lauren C Briere, John H Newman, Brianna M Tucker, Joel B Krier, John Carey, Amanda L Minogue, Frances High, Nichole Hayes, Esteban C Dell'Angelica, Isaac S Kohane, Gabor Marth +347 morecore +1 more sourceNucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression
Biotechnology Journal, Volume 21, Issue 9, September 2026.Graphical Abstract and Lay Summary
Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks +2 morewiley +1 more source
