Results 231 to 240 of about 29,949 (269)

Mitochondrial fission and fusion in inflammatory diseases: mechanisms and therapeutic implications. [PDF]

J Transl Med
Xu W, Xu X, Zhang Y, Li F, Xia D.
europepmc   +1 more source

Mitochondrial Homeostasis in Diabetic Cardiomyopathy: From Dysfunction to Therapeutic Strategies. [PDF]

Antioxidants (Basel)
Huang Y, Zou W, Jiang X, Cheng J, Zheng J.   +4 more
europepmc   +1 more source

Targeting the ARRDC3-DRP1 Axis via hUMSC-Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury. [PDF]

Adv Healthc Mater
Ji R, Zhang Z, Liu Z, Yang K, Mao X, Chu M, Wang Y, Zhao J.   +7 more
europepmc   +1 more source

Extracellular matrix signals promote actin-dependent mitochondrial elongation and activity. [PDF]

iScience
Gatti P, Mukherjee P, Talukdar PD, Freppel W, Kasmaie A, Kanou J, Chatel-Chaix L, Chatterji U, Germain M.   +8 more
europepmc   +1 more source

Mitochondrial Ultrastructure, Fission Proteins, Activity, and Motor Dysfunctions in the Innovative Parkinson's Disease Model Induced by Manganese Inhalation. [PDF]

Toxics
Garcia-Caballero CA, Ordoñez-Librado JL, De Alba-Ríos A, Montiel-Flores E, Aparicio-Trejo OE, García-Arroyo F, Cuevas-Lopez B, Pedraza-Chaverri J, Rodríguez-Lara V, Tron-Alvarez R, Gutierréz-Valdez AL, Sánchez-Betancourt J, Reynoso-Erazo L, Avila-Costa MR.   +13 more
europepmc   +1 more source

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Mechanistic and therapeutic role of Drp1 in the pathogenesis of stroke

Gene, 2023
Stroke had emerged as one of the leading causes of death and long-term disability across the globe. Emerging evidence suggests a significant increase in the incidence of stroke with age, which is further expected to increase dramatically owing to an ever-expanding elderly population.
Himaja, Pegadraju, Joshua, Abby Thomas, Rahul, Kumar   +2 more
openaire   +2 more sources

Drp1 Tubulates the ER in a GTPase-Independent Manner [PDF]

Molecular Cell, 2020
Mitochondria are highly dynamic organelles that continuously grow, divide, and fuse. The division of mitochondria is crucial for human health. During mitochondrial division, the mechano-guanosine triphosphatase (GTPase) dynamin-related protein (Drp1) severs mitochondria at endoplasmic reticulum (ER)-mitochondria contact sites, where peripheral ER ...
Yoshihiro Adachi, Takashi Kato, Tatsuya Yamada   +2 more
exaly   +4 more sources

Drp1 and the cytoskeleton: mechanistic nexus in mitochondrial division

Current Opinion in Physiology, 2022
Dynamin-related protein 1 (Drp1), the master regulator of mitochondrial division (MD), interacts with the cytoskeletal elements, namely filamentous actin (F-actin), microtubules (MT), and septins that coincidentally converge at MD sites. However, the mechanistic contributions of these critical elements to, and their cooperativity in, MD remain poorly ...
Jason A, Mears, Rajesh, Ramachandran
openaire   +2 more sources