Results 11 to 20 of about 83,951 (257)

Xpert MTB/RIF Ultra Assay Using Stool: an Effective Solution for Bacilli Identification from Adult Pulmonary Tuberculosis Suspects without Expectorated Sputum

Microbiology Spectrum, 2023
This study evaluated the diagnostic performance of stool-based Xpert MTB/RIF Ultra assay (Xpert-Ultra, Cepheid, USA) against other tests using respiratory tract specimens (RTS) and stool for diagnosing adult pulmonary tuberculosis. A prospective study on
Xia Yu, Fen Wang, Ruyan Ren, Lingling Dong, Yi Xue, Liping Zhao, Junnan Jia, Hairong Huang   +7 more
doaj   +1 more source

Trends and Species Diversity of Non-tuberculous Mycobacteria Isolated From Respiratory Samples in Northern China, 2014–2021

Frontiers in Public Health, 2022
BackgroundPulmonary non-tuberculous mycobacteria (NTM) infection has become a public health concern in China and around the world. The objective of this study was to describe the longitudinal changes in the frequency and diversity of NTM in northern ...
Qing Sun, Jun Yan, Xinlei Liao, Chaohong Wang, Chenqian Wang, Guanglu Jiang, Lingling Dong, Fen Wang, Hairong Huang, Guirong Wang, Junhua Pan   +10 more
doaj   +1 more source

Extensively drug-resistant tuberculosis [PDF]

The Lancet Infectious Diseases, 2009
Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any fluoroquinolone, and at least one of three injectable second-line drugs (amikacin, capreomycin, or kanamycin).
Mandeep, Jassal, William R, Bishai
openaire   +4 more sources

Comparison of the in vitro activity of linezolid, tedizolid, sutezolid, and delpazolid against rapidly growing mycobacteria isolated in Beijing, China

International Journal of Infectious Diseases, 2021
Background: The natural resistance of rapidly growing mycobacteria (RGM) to multiple antibiotics renders the treatment of the infections caused less successful.
Shu’an Wen, Xiaopan Gao, Weijie Zhao, Fengmin Huo, Guanglu Jiang, Lingling Dong, Liping Zhao, Fen Wang, Xia Yu, Hairong Huang   +9 more
doaj   +1 more source

Extremely high levels of central nervous system involvement in miliary tuberculosis

BMC Infectious Diseases, 2022
Background Miliary tuberculosis (TB) is one of the severest manifestations of TB that can be lethal when concomitant with the central nervous system (CNS) involvement.
Guirong Wang, Ruixia Liang, Qing Sun, Xinlei Liao, Chenqian Wang, Hairong Huang   +5 more
doaj   +1 more source

Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens

Microbiology Spectrum, 2022
Next-generation sequencing (NGS) enables rapid identification of common and rare drug-resistant genetic variations from tuberculosis (TB) patients’ sputum samples and MTB isolates.
Jing Song, Weili Du, Zichen Liu, Jialu Che, Kun Li, Nanying Che   +5 more
doaj   +1 more source

The aceE involves in mycolic acid synthesis and biofilm formation in Mycobacterium smegmatis

BMC Microbiology, 2020
Background The integrity of cell wall structure is highly significant for the in vivo survival of mycobacteria. We hypothesized that changes in morphology may indicate changes in cell wall metabolism and identified an aceE gene mutant (aceE-mut) which ...
Suting Chen, Tianlu Teng, Shuan Wen, Tingting Zhang, Hairong Huang   +4 more
doaj   +1 more source

Non-tuberculous mycobacterial disease: progress and advances in the development of novel candidate and repurposed drugs

Frontiers in Cellular and Infection Microbiology, 2023
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens that can infect all body tissues and organs. In particular, the lungs are the most commonly involved organ, with NTM pulmonary diseases causing serious health issues in patients with ...
Yuzhen Gu, Wenjuan Nie, Hairong Huang, Xia Yu   +3 more
doaj   +1 more source

Managing drug resistant tuberculosis [PDF]

BMJ, 2008
#### Summary points Antituberculosis drug resistance is increasing both in the United Kingdom and internationally.1 2 It has come to greater public attention with the emergence of extensively drug resistant tuberculosis (box 1) in South Africa, where an outbreak proved rapidly fatal among people with advanced HIV infection.3 In this article we review ...
Grant, Alison, Gothard, Philip, Thwaites, Guy   +2 more
openaire   +4 more sources

Drug-resistant tuberculosis

Current Opinion in Pulmonary Medicine, 2013
This review discusses the recent evidence on epidemiology, diagnosis, and treatment of drug-resistant and multidrug-resistant (MDR) tuberculosis (TB), an area where solutions for better diagnosis and treatment continually develop.The prevalence of drug resistance has been constantly rising during the recent years.
Pontali E., Matteelli A., Migliori G. B.
  +7 more sources