Results 41 to 50 of about 811,427 (166)

Effect of Mutation in Efflux Pump Regulatory Protein (MexR) of Pseudomonas aeruginosa: A Bioinformatic Study

Medical Laboratory Journal, 2017
Background and Objectives: Pseudomonas aeruginosa is an important non-fermenting gram-negative hospital-acquired pathogen. Treatment of P. aeruginosa infections has become more challenging due to overexpression of efflux pumps.
Hamid Vaez, Vahid Vaez, Farzad Khademi
doaj  

Resistencia a drogas de segunda línea en cepas peruanas de Mycobacterium tuberculosis multidrogorresistentes

Revista Peruana de Medicina Experimental y Salud Pública
Objetivos. Determinar los perfiles de resistencia de las quinolonas; ciprofloxacina (Cpx), ofloxacina (Ofx), gatifloxacina (Gfx) y moxifloxacina (Mfx), y de los inyectables; kanamicina (Km), amikacina (Am) y capreomicina (Cm) en cepas ...
Francesca Barletta, Carlos Zamudio, Leen Rigouts, Carlos Seas   +3 more
doaj  

Role of epigenetics-microRNA axis in drug resistance of multiple myeloma

Journal of Hematology & Oncology, 2017
Despite administration of novel therapies, multiple myeloma (MM) remains incurable with resistance to drugs leading to relapse in most patients. Thus, it is critical to understand the detailed mechanisms underlying the drug resistance of MM and develop ...
Nasrin Rastgoo, Jahangir Abdi, Jian Hou, Hong Chang   +3 more
doaj   +1 more source

Antibiotic resistance pattern and distribution of Vietnamese extended-spectrum- β lactamase (VEB-1) gene in Acinetobacter baumannii isolated from hospitalized patients in Kashan Shahid Beheshti hospital during 2013-2014

Fiyz̤, 2017
Background: Acinetobacter baumannii are widely distributed pathogens in hospitals. They have the ability to have various mechanisms of resistance. Multiple drug resistant (MDR) strains of A. baumannii have created therapeutic problems worldwide.
Nahid Madadi-Goli , Rezvan Moniri , Sareh Bagheri-Josheghani   +2 more
doaj  

MicroRNA-665 and its potential role in drug response and survival outcomes in multiple myeloma: a preliminary study

Frontiers in Pharmacology
BackgroundMultiple myeloma (MM) is a complex hematological malignancy with heterogeneous clinical and pathophysiological backgrounds that influence treatment responses and outcomes.
Rui Bergantim, Rui Bergantim, Rui Bergantim, Rui Bergantim, Sara Peixoto da Silva, Sara Peixoto da Silva, Sara Peixoto da Silva, Vanessa Pinto, Vanessa Pinto, Joana M. Pereira, Joana M. Pereira, Diana Sousa, Diana Sousa, Diana Sousa, Fernanda Trigo, Rune Matthiesen, José E. Guimarães, José E. Guimarães, José E. Guimarães, José E. Guimarães, José E. Guimarães, M. Helena Vasconcelos, M. Helena Vasconcelos, M. Helena Vasconcelos   +23 more
doaj   +1 more source

Yin Yang 1 (YY1) as a Central Node in Drug Resistance Pathways: Potential for Combination Strategies in Cancer Therapy

Biomolecules
Tumor drug resistance, a major cause of treatment failure, involves complex multi-gene networks, remodeling of signaling pathways, and interactions with the tumor microenvironment.
Zhiyan Li, Xiang Jia, Ian Timothy Sembiring Meliala, Yanjun Li, Vivi Kasim   +4 more
doaj   +1 more source

Tuberculose resistente: revisão molecular

Revista de Saúde Pública
O progresso na compreensão dos mecanismos de resistência aos fármacos usados no tratamento da tuberculose tem permitido o desenvolvimento de novos métodos para a detecção da tuberculose resistente.
Maria Lúcia Rosa Rossetti, Andréia Rosane de Moura Valim, Márcia Susana Nunes Silva, Vívian Sumnienski Rodrigues   +3 more
doaj  

Prevalence of Multiple Antibiotic Resistance Among Salmonella Isolates from Clinical Samples in Dhaka, Bangladesh

Oman Medical Journal
Objectives: Antibiotic resistance in clinical isolates is often correlated to poor disease management or prolonged hospitalization. The study aimed to determine the prevalence of multidrug-resistant (MDR) Salmonella isolates in clinical samples collected
Rashed Imtiaz, Protyaee Saha, Esfat M. Saim Brishty, Sadia Kamal, Manik Chandra Shill, Hasan Mahmud Reza, Preeti Jain   +6 more
doaj   +1 more source

Multiple drug resistant tuberculosis. [PDF]

Journal of Clinical Pathology, 1997
F A, Drobniewski, M D, Yates
openaire   +2 more sources

Targeting of SKP2 to combat drug resistance in multiple myeloma

Scientific Reports
Multiple myeloma (MM) is an incurable plasma cell malignancy in which drug resistance remains a significant limitation to treatment. SKP2, the substrate-recognition component of the SCF-SKP2 ubiquitin-protein ligase complex, plays a critical role in the ...
Omar Faruq, Jane Ngo, Deepak Iyer, Jonahunnatha Nesson, Mariusz Shrestha, Hong Chang   +5 more
doaj   +1 more source