Results 41 to 50 of about 2,744,410 (300)

Persister cells as a possible cause of antibiotic therapy failure in Helicobacter pylori

open access: yesJGH Open, 2021
Background and Aim Due to the failure of antibiotic treatment and recurrence of infection in patients with Helicobacter pylori, this study was designed to find the possible cause of treatment failure and recurrence of the H.
Parvin Bahmaninejad   +5 more
doaj   +1 more source

Ketoconazole induces reversible antifungal drug tolerance mediated by trisomy of chromosome R in Candida albicans. [PDF]

open access: yesFront Microbiol
BackgroundThe emergence of tolerance to antifungal agents in Candida albicans complicates the treatment of fungal infections. Understanding the mechanisms underlying this tolerance is crucial for developing effective therapeutic strategies.ObjectiveThis ...
Zheng L, Xu Y, Wang C, Guo L.
europepmc   +2 more sources

Induction of Aspergillus fumigatus zinc cluster transcription factor OdrA/Mdu2 provides combined cellular responses for oxidative stress protection and multiple antifungal drug resistance

open access: yesmBio, 2023
Zinc cluster transcription factors (Zcfs) encoding zcf genes are exclusive for fungi and required for multiple cellular processes including metabolism and development.
Christoph Sasse   +13 more
doaj   +1 more source

Tolerance of Muslim beliefs and practices: Age related differences and context effects [PDF]

open access: yes, 2007
Tolerant judgments of Muslims’ political rights and dissenting beliefs and practices by ethnic Dutch adolescents (12–18 years) were examined. Participants (N = 632) made judgments of different types of behaviors and different contexts in an experimental ...
Slooter, Luuk   +3 more
core   +2 more sources

Drug-Tolerant Idling Melanoma Cells Exhibit Theory-Predicted Metabolic Low-Low Phenotype

open access: yesFrontiers in Oncology, 2020
Cancer cells adjust their metabolic profiles to evade treatment. Metabolic adaptation is complex and hence better understood by an integrated theoretical-experimental approach. Using a minimal kinetic model, we predicted a previously undescribed Low/Low (
Dongya Jia   +17 more
doaj   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

open access: yes, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Evaluation of the Peer Support Program (Student Drug Prevention) 1986-1987

open access: yes, 2019
The Peer Support program is a school based program funded by the National Campaign Against Drug Abuse (NCADA) as a drug prevention strategy. Prior to the existence of the NCADA the program was funded through the NSW Drug and Alcohol Authority.
Directorate of the Drug Offensive
core   +1 more source

In vivo laboratory practicals in research-led teaching: An example using glucose tolerance tests in lean and obese mice [PDF]

open access: yes, 2011
The use of animal models is an essential part of medical research and drug development. The essential skills required to be able to do such research includes experimental design, statistical analysis and the actual handling and treating of the animals ...
Ian M. Kinchin   +10 more
core   +1 more source

Western Hemisphere Drug Policy Commission [website]

open access: yes, 2021
Website of the Western Hemisphere Drug Policy Commission (WHDPC), charged to "evaluate a range of US counternarcotics programs in the Americas and then make recommendations to improve them" -- including a recording and transcript of the group's hearing ...
United States. Western Hemisphere Drug Policy Commission.
core  

Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs) : a systematic structured review of the literature [PDF]

open access: yes, 2007
Adverse events triggered by non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common drug-related intolerance reactions in medicine; they are possibly related to inhibition of cyclooxygenase-1.
Weberschock, Tobias Bernd Bernd   +8 more
core   +1 more source

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