Results 41 to 50 of about 2,900,874 (198)

A DNA element regulates drug tolerance and withdrawal in Drosophila. [PDF]

open access: yes, 2013
Drug tolerance and withdrawal are insidious responses to drugs of abuse; the first increases drug consumption while the second punishes abstention. Drosophila generate functional tolerance to benzyl alcohol sedation by increasing neural expression of the
Jascha B Pohl   +17 more
core   +2 more sources

Molecular control of Acinetobacter baumannii biofilm development and persistence

open access: yesO Mundo da Saúde
Acinetobacter baumannii is a critical nosocomial pathogen whose persistence is closely linked to biofilm-associated survival. This narrative review critically examined structural determinants, regulatory networks, evidence strength, and intervention ...
Erda Syawati Dakim   +6 more
doaj   +1 more source

Employee involvement in and perceptions of campus alcohol and drug abuse prevention programming at UW-Stout [PDF]

open access: yes, 1999
Plan BNational research has continually shown that college campuses nationwide foster many alcohol and drug use behaviors. It is suggested that faculty and staff may hold several misperceptions in regard to the prevalence and nature of the alcohol and ...
Mishacoff, Natascha L.
core  

Extreme Drug Tolerance of Mycobacterium abscessus “Persisters”

open access: yesFrontiers in Microbiology, 2020
Persistence of infection despite extensive chemotherapy with antibiotics displaying low MICs is a hallmark of lung disease caused by Mycobacterium abscessus (Mab). Thus, the classical MIC assay is a poor predictor of clinical outcome.
Yee-Kuen Yam   +5 more
doaj   +1 more source

The relation between drug exposure and tolerance: contingent drug tolerance reexamined

open access: yes, 1994
The finding that the performance of a response during periods of drug exposure facilitates the development of tolerance to the effects of the drug on that response is commonly referred to as contingent drug tolerance.
Kippin, Tod Edward
core   +1 more source

Evaluation of the Peer Support Program (Student Drug Prevention) 1986-1987

open access: yes, 2019
The Peer Support program is a school based program funded by the National Campaign Against Drug Abuse (NCADA) as a drug prevention strategy. Prior to the existence of the NCADA the program was funded through the NSW Drug and Alcohol Authority.
Directorate of the Drug Offensive
core   +1 more source

Drug Tolerance in Mycobacterium tuberculosis [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1999
ABSTRACT Although Mycobacterium tuberculosis is eradicated rapidly during therapy in some patients with pulmonary tuberculosis, it can persist for many months in others. This study examined the relationship between mycobacterial drug tolerance (delayed killing in vitro), persistence, and relapse.
R S, Wallis   +14 more
openaire   +2 more sources

Progress in the study of autophagy-related proteins affecting resistance to chemotherapeutic drugs in leukemia

open access: yesFrontiers in Cell and Developmental Biology
Leukemia is a life-threatening malignant tumor of the hematopoietic system. Currently, the main treatment modalities are chemotherapy and hematopoietic stem cell transplantation. However, increased drug resistance due to decreased sensitivity of leukemia
Meng Li   +8 more
doaj   +1 more source

Observational multicenter study of efficacy of paroxetine film-coated tablet in the treatment of anxiety disorder [PDF]

open access: yesMedicinski Glasnik, 2018
Aim To examine the efficiency of paroxetine treatment of anxiety disorders in adult patients over the period of 12 months and the improvement of symptoms of anxiety disorder during this period, as well as to examine the tolerability of the administered ...
Alma Džubur Kulenović   +7 more
doaj   +1 more source

Tolerability and safety of antifungal drugs

open access: yesReviews in Health Care, 2013
When treating critically ill patients, as those with fungal infections, attention should be focused on the appropriate use of drugs, especially in terms of dose, safety, and tolerability. The fungal infection itself and the concomitant physiological disorders concur to increase the risk of mortality in these patients, therefore the use of any ...
openaire   +3 more sources

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