During an oral glucose tolerance test (OGTT) glucose and insulin levels were measured in 26 patients with prolactin-producing pituitary tumours without growth hormone excess.
A. Renauld +24 more
core +1 more source
Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs
Previously, we identified long repeat sequences that are frequently associated with genome rearrangements, including copy number variation (CNV), in many diverse isolates of the human fungal pathogen Candida albicans (Todd et al., 2019).
Robert T Todd, Anna Selmecki
doaj +1 more source
SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania +19 more
core +1 more source
Anthelmintic tolerance in free-living and facultative parasitic isolates of Halicephalobus (Panagrolaimidae) [PDF]
Studies on anthelmintic resistance in equine parasites do not include facultative parasites. Halicephalobus gingivalis is a free-living bacteriovorous nematode and a known facultative parasite of horses with a strong indication of some form of tolerance ...
Andrássy +18 more
core +1 more source
Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance [PDF]
Alfredo Ghezzi, Harish R. Krishnan, Linda Lew, Francisco J. Prado III, Darryl S. Ong, Nigel S. Atkinson, Section of Neurobiology and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas, United States of ...
Atkinson, Nigel S. +5 more
core +3 more sources
Ethanol reversal of tolerance to the respiratory depressant effects of morphine [PDF]
Opioids are the most common drugs associated with unintentional drug overdose. Death results from respiratory depression. Prolonged use of opioids results in the development of tolerance but the degree of tolerance is thought to vary between different ...
A Fugelstad +62 more
core +5 more sources
Depth of anesthesia control using internal model control techniques [PDF]
The major difficulty in the design of closed-loop control during anaesthesia is the inherent patient variability due to differences in demographic and drug tolerance.
Anna, Shahab, Wen, Peng
core +2 more sources
Bacterial persistence has become a worldwide health problem due to its ability to cause the recalcitrance and relapse of infections. The existence of bacterial persistence and their possible mechanisms have been widely reported.
Junzhuo Lu +9 more
doaj +1 more source
KDM5A and KDM5B histone-demethylases are overexpressed in many cancers and have been involved in drug tolerance. Here, we describe that KDM5A, together with KDM5B, contribute to replication stress (RS) response and tolerance.
Solenne Gaillard +8 more
doaj +1 more source
Methionine Adenosyltransferase 1a (MAT1A) Enhances Cell Survival During Chemotherapy Treatment and is Associated with Drug Resistance in Bladder Cancer PDX Mice. [PDF]
Bladder cancer is among the top ten most common cancers, with about ~380,000 new cases and ~150,000 deaths per year worldwide. Tumor relapse following chemotherapy treatment has long been a significant challenge towards completely curing cancer.
de Vere White, Ralph +8 more
core +2 more sources

