Results 211 to 220 of about 114,219 (358)

Halymenia durvillei Extracts Exert Antiobesity Effects by Targeting hosl‐1‐Mediated Lipolysis in a Glucose‐Induced Caenorhabditis elegans Model

open access: yeseFood, Volume 6, Issue 3, June 2025.
This study demonstrates the antiobesity potential of Halymenia durvillei (H. durvillei) extracts using a Caenorhabditis elegans (C. elegans) obesity model. The extracts significantly reduced total fat accumulation, lowered reactive oxygen species (ROS) levels, and extended the lifespan in glucose‐fed C. elegans. These beneficial effects may be mediated
Kawita Chumphoochai   +8 more
wiley   +1 more source

Skin microbiome engineering: Challenges and opportunities in skin diseases treatment

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley   +1 more source

The Fate of dsRNA in the Nucleus [PDF]

open access: bronze, 2001
Zuo‐Feng Zhang, Gordon Carmichael
openalex   +1 more source

Viral metagenomics of Okavango Delta water pans reveal novel insights into wildlife disease potential

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
Botswana's Seronga region saw a mass elephant die‐off potentially linked to water sources. This study analyzes Okavango Delta metagenomes, uncovering a diversity of viruses and harmful pathogens. Findings highlight the importance of understanding viral ecology in these waters and support One Health's objective in protecting human, animal, and ecosystem
Emilie J. Skoog   +8 more
wiley   +1 more source

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

open access: green, 1998
Siddharth Balachandran   +5 more
openalex   +2 more sources

Loss of Adenosine Deaminase Acting on RNA 1 Induces Panoptosis and Immune Response in Ulcerative Colitis Gut Mucosa

open access: yesMedComm, Volume 6, Issue 6, June 2025.
The gut virome is a complex community that, when disrupted, may contribute to inflammatory diseases like IBD. We found that ADAR1 expression is reduced in gut inflamed mucosa of ulcerative colitis patients. ADAR1 silencing heightened activation of inflammatory pathways and PANoptosis exacerbating gut tissue damage, but JAK inhibition or AhR activation ...
Andrea Iannucci   +13 more
wiley   +1 more source

RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencing.

open access: yes, 2013
The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult
Bueno i Torrens, David, 1965-   +1 more
core  

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