Results 221 to 230 of about 114,219 (358)

Recent Advances in Cotton Transformation and Genome Editing Techniques: The Prospects and Challenges

open access: yesModern Agriculture, Volume 3, Issue 1, June 2025.
Application of transformed cotton plants. Cotton transformation yields desirable traits, including: (1) strengthening insect and pest resistance, (2) enhancing the resistance to abiotic stress such as drought, heat, cold and salinity, (3) improving herbicide tolerance, (4) increasing the cotton lint and seed yield, (5) boosting nutrient uptake ...
Oluwaseun Olayemi Aluko   +8 more
wiley   +1 more source

A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA

open access: yesMolecular Therapy: Nucleic Acids, 2019
M. Baiersdörfer   +6 more
semanticscholar   +1 more source

Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang   +4 more
wiley   +1 more source

Functional implications of hexameric dynamics in SARS‐CoV‐2 Nsp15

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract SARS‐CoV‐2, the virus responsible for the COVID‐19 pandemic, has undergone continuous evolution, leading to the emergence of variants with altered transmissibility and immune evasion. For the non‐structural proteins (Nsps) of SARS‐CoV‐2, there are limited structural analyses of their naturally occurring mutations.
Manashi Sonowal   +18 more
wiley   +1 more source

Identification, validation, and characterization of approved and investigational drugs interfering with the SARS‐CoV‐2 endoribonuclease Nsp15

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou   +13 more
wiley   +1 more source

dsRNA-ACTIVATED PROTEIN KINASE (PKR) MEDIATES VIRAL PRIMING OF LETHALITY IN POLYMICROBIAL SEPSIS, [PDF]

open access: bronze, 2002
Leslie Doughty   +5 more
openalex   +1 more source

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