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Archives of Biochemistry and Biophysics, 2016
Double stranded RNA (dsRNA) participates in several biological processes, where RNA molecules acquire secondary structure inside the cell through base complementarity. The double stranded RNA binding domain (dsRBD) is one of the main protein folds that is able to recognize and bind to dsRNA regions. The N-terminal dsRBD of DCL1 in Arabidopsis thaliana (
Drusin, Salvador Iván +4 more
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Double stranded RNA (dsRNA) participates in several biological processes, where RNA molecules acquire secondary structure inside the cell through base complementarity. The double stranded RNA binding domain (dsRBD) is one of the main protein folds that is able to recognize and bind to dsRNA regions. The N-terminal dsRBD of DCL1 in Arabidopsis thaliana (
Drusin, Salvador Iván +4 more
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2011
Several families of viruses have segmented genomes with 3-12 chromosomes. They are capable of packaging these segments in a precise manner so that each virus particle contains one each of the genomic segments. The Cystoviridae are a family of bacteriophages that contain three genomic segments of dsRNA.
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Several families of viruses have segmented genomes with 3-12 chromosomes. They are capable of packaging these segments in a precise manner so that each virus particle contains one each of the genomic segments. The Cystoviridae are a family of bacteriophages that contain three genomic segments of dsRNA.
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dsRNA Inhibits Protein Expression
Science's STKE, 2000The ability of double-stranded RNA (dsRNA) to block gene expression is termed RNA interference (RNAi). RNAi has been identified in Drosophila, Caenorhabditis , and other organisms as a way to suppress transposition and to silence endogenous genes.
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2001
RNAi and Cosuppression: Double-Stranded RNA as an Agent of Sequence-Specific Genetic Silencing in Animals and Plants, Jeffrey A. Norman and Mary K. Montgomery The Double-Stranded RNA-Activated Protein Kinase PKR, Randal J. Kaufman The Double-Stranded RNA Viruses of Saccharomyces Cerevisiae, Reed B. Wickner, Juan Carlos Ribas, and Anjanette Searfoss The
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RNAi and Cosuppression: Double-Stranded RNA as an Agent of Sequence-Specific Genetic Silencing in Animals and Plants, Jeffrey A. Norman and Mary K. Montgomery The Double-Stranded RNA-Activated Protein Kinase PKR, Randal J. Kaufman The Double-Stranded RNA Viruses of Saccharomyces Cerevisiae, Reed B. Wickner, Juan Carlos Ribas, and Anjanette Searfoss The
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Science's STKE, 2001
Members of the Toll-like receptor (TLR) family appear to recognize molecular patterns found on pathogens. Alexopoulou et al. have found that double-stranded RNA (dsRNA), which can be associate with viral infection, is recognized by TLR3. DsRNA-treated HEK293 cells that expressed TLR3 showed increased activity of the
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Members of the Toll-like receptor (TLR) family appear to recognize molecular patterns found on pathogens. Alexopoulou et al. have found that double-stranded RNA (dsRNA), which can be associate with viral infection, is recognized by TLR3. DsRNA-treated HEK293 cells that expressed TLR3 showed increased activity of the
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Science's STKE, 2006
CD14 is a glycosylphosphatidylinositol (GPI)-anchored pattern recognition receptor that is involved in activation of Toll-like receptors (TLRs) at the cell surface (see Finberg and Kurt-Jones). For example, it binds to lipopolysaccharide (LPS) and viruses to present these foreign agents to TLR4 and TLR2, respectively. Lee et al.
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CD14 is a glycosylphosphatidylinositol (GPI)-anchored pattern recognition receptor that is involved in activation of Toll-like receptors (TLRs) at the cell surface (see Finberg and Kurt-Jones). For example, it binds to lipopolysaccharide (LPS) and viruses to present these foreign agents to TLR4 and TLR2, respectively. Lee et al.
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2019
This chapter describes the practical value for attempting to detect and describes the double-stranded (dsRNAs) lies in the ease with which they can be isolated and characterized. Most diagnostic laboratories recognize the value of less specific tests which can be used in addition to specific tests in the early testing stages, especially when the ...
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This chapter describes the practical value for attempting to detect and describes the double-stranded (dsRNAs) lies in the ease with which they can be isolated and characterized. Most diagnostic laboratories recognize the value of less specific tests which can be used in addition to specific tests in the early testing stages, especially when the ...
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Future Virology, 2007
This symposium series started in 1982 and has taken place every 3 years since, bringing together scientists from all over the world with specific research interests in viruses with a double-stranded (ds) RNA genome belonging to the families of Reoviridae, Cystoviridae, Birnaviridae, Totiviridae, Partitiviridae, Chrysoviridae, Hypoviridae and the genus ...
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This symposium series started in 1982 and has taken place every 3 years since, bringing together scientists from all over the world with specific research interests in viruses with a double-stranded (ds) RNA genome belonging to the families of Reoviridae, Cystoviridae, Birnaviridae, Totiviridae, Partitiviridae, Chrysoviridae, Hypoviridae and the genus ...
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dsRNA-induced mRNA degradation
Trends in Microbiology, 1999Expression of double stranded RNA (dsRNA) in Caenorhabditis elegans has been shown, under certain circumstances, to cause genetic interference. In plants, expression of RNA leads to phenotypic co-suppression. However, the use of dsRNA to manipulate microorganisms genetically is still in its infancy.
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dsRNA analyzer: a bioinformatic tool for targeted dsRNA design in arthropods
The growing interest for environmentally safe and species-selective pest control strategies has positioned RNA interference (RNAi) as a promising mechanism for targeted pest suppression. An emerging strategy in this approach employs double stranded RNA (dsRNA) as the low-risk pesticide (LRP) of choice.Andronis, Christos +2 more
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