Results 91 to 100 of about 43,287 (283)
Cytoskeleton, EarlyView.ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves +3 more
wiley +1 more source
Dynamics of Allosteric Transitions in Dynein [PDF]
Structure, 2018 1SummaryCytoplasmic Dynein, a motor with an unusual architecture made up of a motor domain belonging to the AAA+ family, walks on microtubule towards the minus end. Prompted by the availability of structures in different nucleotide states, we performed simulations based on a new coarse-grained model to illustrate the molecular details of the dynamics ...
Goldtzvik, Yonathan +2 more
openaire +4 more sources
Making Two out of One: Kinesin Motors Driving Plant Cell Division
Cytoskeleton, EarlyView.ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley +1 more source
Reconstitution of dynein transport to the microtubule plus end by kinesin
eLife, 2014 Cytoplasmic dynein powers intracellular movement of cargo toward the microtubule minus end. The first step in a variety of dynein transport events is the targeting of dynein to the dynamic microtubule plus end, but the molecular mechanism underlying this
Anthony J Roberts +2 more
doaj +1 more source
Dynein’s directionality is controlled by the angle and length of its stalk
Nature, 2019 The ability of cytoskeletal motors to move unidirectionally along filamentous tracks is central to their role in cargo transport, motility and cell division.
Sinan Can +4 more
semanticscholar +1 more source
Human dynein and sperm pathology. [PDF]
The Journal of cell biology, 1981 Human spermatozoa with normal structure and with different axonemal deficiencies (absence of axoneme, of arms, or of central structures) were studied by electron microscopy, SDS-polyacrylamide gel electrophoresis, and ATPase activity measurements. Normal human sperm possess a complement of high molecular weight polypeptides with an electrophoretic ...
BACCETTI, B. +3 more
openaire +5 more sources
Cytoskeleton, EarlyView.ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas +5 more
wiley +1 more source
HIV-1 Engages a Dynein-Dynactin-BICD2 Complex for Infection and Transport to the Nucleus
Journal of Virology, 2018 During HIV-1 infection, the virus must travel across the cytoplasm to enter the nucleus. The host cell motor protein complex dynein has been implicated in HIV-1 intracellular transport. We show that expression of the dynein heavy chain, components of the
Stephanie K. Carnes +2 more
semanticscholar +1 more source
The Journal of Cell Biology, 2007 Dynein has finally found a partner with direction. On page 1005, Griffis et al. identify a cofactor for the motor that seems to bring it to kinetochores and only kinetochores. Figure 1 Spindly (green) is enriched on kinetochores (red) that are not yet aligned on the metaphase plate.
openaire +2 more sources
The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains
Cytoskeleton, EarlyView.ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell +4 more
wiley +1 more source