Results 81 to 90 of about 13,944,920 (244)
Long-term effect of early-life stress from earthquake exposure on working memory in adulthood
, 2015 Na Li,1-3* Yumei Wang,1-3* Xiaochuan Zhao,1-3 Yuanyuan Gao,1-3 Mei Song,1-3 Lulu Yu,1-3 Lan Wang,1-3 Ning Li,1-3 Qianqian Chen,1-3 Yunpeng Li,1-3 Jiajia Cai,1-3 Xueyi Wang1-31Department of Psychiatry, The ...
Yu L +10 more
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Adverse effects of early-life stress: focus on the rodent neuroendocrine system
Neural Regeneration ResearchEarly-life stress is associated with a high prevalence of mental illnesses such as post-traumatic stress disorders, attention-deficit/hyperactivity disorder, schizophrenia, and anxiety or depressive behavior, which constitute major public health problems.
Seung Hyun Lee, Eui-Man Jung
doaj +1 more source
Neurobiology of Stress, 2018 Early adversity in childhood increases the risk of anxiety, mood, and post-traumatic stress disorders in adulthood, and specific gene-by-environment interactions may increase risk further.
Hanke Heun-Johnson, Pat Levitt
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Early life stress and altered social behaviors: A perspective across species
Neuroscience ResearchChildhood and adolescent affiliations guide how individuals engage in social relationships throughout their lifetime and adverse experiences can promote biological alterations that facilitate behavioral maladaptation.
Lyonna F. Parise +2 more
doaj +1 more source
The long-term impact of adverse caregiving environments on epigenetic modifications and telomeres
Frontiers in Behavioral Neuroscience, 2015 Early childhood is a sensitive period in which infant-caregiver experiences have profound effects on brain development and behavior. Clinical studies have demonstrated that infants who experience stress and adversity in the context of caregiving are at ...
Jennifer eBlaze +2 more
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Als Zusammenfassung der diesjährigen Konferenzinhalte zum Leitthema „Ressourcen – Grundlagen für einen guten Start ins Leben“ dürfen wir Ihnen diesen Abstractband übermitteln.
Paracelsus Medizinische Universität. Institut für Early Life Care
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Resistance to early-life stress in mice: effects of genetic background and stress duration
Frontiers in Behavioral Neuroscience, 2011 Early-life stress can induce marked behavioural and physiological impairments in adulthood including cognitive deficits, depression, anxiety and gastrointestinal dysfunction. Although robust rat models of early-life stress exist there are few established
Helene M. Savignac +4 more
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source