Results 91 to 100 of about 21,210 (293)
Effectiveness of an antifungal stewardship programme at a London teaching hospital 2010–16 [PDF]
Background The need for antifungal stewardship is gaining recognition with increasing incidence of invasive fungal infection (IFI) and antifungal resistance alongside the high cost of antifungal drugs.
Al-Ghusein, H+9 more
core +1 more source
Echinocandin resistance in Candida is a great concern, as the echinocandin drugs are recommended as first-line therapy for patients with invasive candidiasis. Here, we review recent advances in our understanding of the epidemiology, underlying mechanisms, methods for detection and clinical implications.Echinocandin resistance has emerged over the ...
Maiken Cavling Arendrup, David S. Perlin
openaire +3 more sources
Candida parapsilosis associated with cervical necrotizing fasciitis and descending mediastinitis [PDF]
published_or_final_versio
Chan, YW, Choi, WK, Lee, CC
core +1 more source
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation [PDF]
We thank Cowen lab members for helpful discussions. We also thank David Rogers (University of Tennessee) for sharing microarray analysis of the CAS5 homozygous mutant, and Li Ang (University of Macau) for assistance in optimizing the ChIP-Seq experiments.
Andrews, Brenda J+18 more
core +2 more sources
In Vitro Interactions of Echinocandins with Triazoles Against Multidrug-Resistant Candida auris
We determined the in vitro interactions between echinocandins and azoles against 10 multidrug-resistant Candida auris strains by use of a microdilution checkerboard technique.
H. Fakhim+6 more
semanticscholar +1 more source
Echinocandins for candidemia: a rational choice
Among antifungal drugs, echinocandins (micafungin, caspofungin and anidulafungin) represent a rational choice for the first-line therapy of candidemia/invasive candidiasis in critically ill patients. Among other properties characterizing echinocandins, it’s important to emphasize the broad spectrum of activity, the fungicidal activity against the ...
Menichetti, Francesco+1 more
openaire +4 more sources
Review of the guidelines for the treatment and prevention of invasive candidiasis in newborns and children [PDF]
nvasive infections caused by Candida species are the most common invasive fungal infections in children of different age groups. Premature neonates, especially newborns with low and extremely low birth-weight, have very high mortality rates, with the ...
Veselov A.V.
doaj
New strategic insights into managing fungal biofilms [PDF]
Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa+6 more
core +3 more sources
Schematic illustration of prepared poly(DEAEMA‐co‐EMA)/PIN composities and 3D AFM image. Abstract In the current study, in the first stage, amphiphilic poly(2‐diethylamino ethylmethacrylate‐co‐ethyl methacrylate) [Poly(DEAEMA‐co‐EMA)] was synthesized from the 2‐diethylamino ethylmethacrylate (DEAEMA) and the ethyl methacrylate (EMA) using the free ...
Safiye Elif Korcan+4 more
wiley +1 more source
Reviews Of Anti‐infective Agents: Anidulafungin: A Novel Echinocandin [PDF]
Until recently, the treatment available for serious fungal infections was composed of amphotericin B and azoles, and each class demonstrated significant limitations. Echinocandins are a new class of drugs that have shown promising results in treating a variety of fungal infections.
Jose A. Vazquez, Jack D. Sobel
openaire +3 more sources