Targeting the integrated stress response or Ataxin-2 alleviates neurodegeneration in PolyGR models of C9orf72 associated frontotemporal dementia and amyotrophic lateral sclerosis. [PDF]
Acta Neuropathol CommunHarper NS +12 more
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Tuning tRNA synthetase inhibition reveals parabolic induction of stress granules limited in size and RNA content. [PDF]
RNABaymiller M, Helton NS, Dodd B, Moon SL.
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Structural insights into HRI kinase activity and inhibition. [PDF]
Biochem Soc TransCao M, Masson GR.
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Effects of the combination of brefeldin A and tunicamycin on endoplasmic reticulum stress and apoptosis in human normal hepatocytes. [PDF]
Curr Res ToxicolYang Y +7 more
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Stress-activated pathways mediate PFAS effects on human placental syncytiotrophoblast cells. [PDF]
Toxicol SciKozai K, Varberg KM.
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Narrative review of rationale for IV deferoxamine plus intranasal insulin to ameliorate brain damage following resuscitation from cardiac arrest. [PDF]
Resusc PlusWhite BC +6 more
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Eukaryotic initiation factor 3d regulates context-dependent pain hypersensitivity through the integrated stress response. [PDF]
Neurobiol PainMian SM +8 more
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Unfolded Protein Response in Glioblastoma: Mechanisms of Proteostasis, Tumor Adaptation, and Therapeutic Relevance. [PDF]
Neurochem ResCaglar HO.
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The integrated stress response in cancer: mechanisms of tumor adaptation and therapeutic targeting. [PDF]
Biochem Soc TransMaldonado E, McIsaac E, Ursini-Siegel J.
europepmc +1 more source
The Bufei Nashen Pill Alleviates COPD by Targeting Endoplasmic Reticulum Stress Through the PERK/eIF2α Signaling Pathway. [PDF]
Immun Inflamm DisHe T, Zhang A, Zhang C.
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