The Venom Proteome of the Ecologically Divergent Australian Elapid, Southern Death Adder <i>Acanthophis antarcticus</i>. [PDF]
Tasoulis T +7 more
europepmc +3 more sources
Electrical Cell Impedance Sensing (ECIS): Feasibility of a Novel In Vitro Approach to Studying Venom Toxicity and Potential Therapeutics. [PDF]
Snakebite envenoming is often discussed in terms of lethality and limb loss, but local tissue injury and coagulotoxic effects of venom are significantly more common acute manifestations of snakebite envenoming (SBE).
Choudhury A +7 more
europepmc +2 more sources
Activity of two key toxin groups in Australian elapid venoms show a strong correlation to phylogeny but not to diet. [PDF]
Tasoulis T +5 more
europepmc +3 more sources
Pro‐inflammatory activities in elapid snake venoms [PDF]
Snake venoms from the genera Micrurus (M. ibiboboca and M. spixii) and Naja (N. naja, N. melanoleuca and N. nigricollis) were analysed, using biological and immunochemical methods, to detect pro‐inflammatory activities, cobra venom factor (COF), proteolytic enzymes, thrombin‐like substances, haemorrhagic and oedema‐producing substances.
Denise V. Tambourgi +5 more
openalex +4 more sources
Aligning Post-Column ESI-MS, MALDI-MS, and Coagulation Bioassay Data of <i>Naja</i> spp., <i>Ophiophagus hannah</i>, and <i>Pseudonaja textillis</i> Venoms Chromatographically to Assess MALDI-MS and ESI-MS Complementarity with Correlation of Bioactive Toxins to Mass Spectrometric Data. [PDF]
Snakebite is a serious health issue in tropical and subtropical areas of the world and results in various pathologies, such as hemotoxicity, neurotoxicity, and local swelling, blistering, and tissue necrosis around the bite site.
Xu H +7 more
europepmc +2 more sources
ACETYLCHOLINESTERASE ISOZYMES FROM ELAPID VENOMS
Su-Ray Lee, W.B. Elliott
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Non-conventional toxins from Elapid venoms
Non-conventional toxins constitute a poorly characterized class of three-finger toxins isolated exclusively from Elapidae venoms. These toxins are monomers of 62-68 amino acid residues and contain five disulfide bridges. However, unlike alpha/kappa-neurotoxins and kappa-neurotoxins which have the fifth disulfide bridge in their middle loop (loop II ...
Selvanayagam Nirthanan +4 more
openalex +5 more sources
Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins [PDF]
Animal venom components are of considerable interest to researchers across a wide variety of disciplines, including molecular biology, biochemistry, medicine, and evolutionary genetics. The three-finger family of snake venom peptides is a particularly interesting and biochemically complex group of venom peptides, because they are encoded by a large ...
Bryan G. Fry +6 more
openalex +5 more sources
High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms. [PDF]
Venoms comprise highly sophisticated bioactive molecules modulating ion channels, receptors, coagulation factors, and the cellular membranes. This array of targets and bioactivities requires advanced high-content bioassays to facilitate the development ...
Kramer S +6 more
europepmc +2 more sources
Immunoreactivity of eastern small eyed snake (Cryptophis nigrescens) venom towards species‐specific antibodies of five medically important venomous Australian elapids [PDF]
The eastern small eyed snake (Cryptophis nigrescens; CN) is an uncommon cause of snakebite in Australia despite the widespread distribution of the snake along the east coast of Australia. Diagnosis of envenomation relies on identification of the snake which is often not possible with animal snakebite cases.
AM Padula
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