Identification of presynaptic neurotoxin complexes in the venoms of three Australian copperheads (Austrelaps spp.) and the efficacy of tiger snake antivenom to prevent or reverse neurotoxicity [PDF]
, 2011 The venom of the Australian lowlands copperhead, Austrelaps superbus, produces significant and potentially lethal neurotoxic paralysis in cases of clinical envenomation. However, little is known about the neurotoxic components within this venom or venoms
Marcon, F, Nicholson, GM
core +1 more source
PLoS Neglected Tropical Diseases, 2016 Snakebite envenomation is a serious medical problem in many tropical developing countries and was considered by WHO as a neglected tropical disease.
Kavi Ratanabanangkoon +8 more
doaj +1 more source
Stabilising the Integrity of Snake Venom mRNA Stored under Tropical Field Conditions Expands Research Horizons. [PDF]
, 2016 BACKGROUND Snake venoms contain many proteinaceous toxins that can cause severe pathology and mortality in snakebite victims. Interestingly, mRNA encoding such toxins can be recovered directly from venom, although yields are low and quality is unknown ...
Logan, Rhiannon
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Polyamines as Snake Toxins and Their Probable Pharmacological Functions in Envenomation
Toxins, 2016 While decades of research have focused on snake venom proteins, far less attention has been paid to small organic venom constituents. Using mostly pooled samples, we surveyed 31 venoms (six elapid, six viperid, and 19 crotalid) for spermine, spermidine ...
Steven D. Aird +3 more
doaj +1 more source
Investigating Toxin Diversity and Abundance in Snake Venom Proteomes
Frontiers in Pharmacology, 2022 Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development.
Theo Tasoulis +2 more
doaj +1 more source
Toxinology of Venoms from Five Australian Lesser Known Elapid Snakes [PDF]
Basic & Clinical Pharmacology & Toxicology, 2012 AbstractResearch into Australian elapid venoms has mainly focused on the seven genera of greatest clinical significance: Acanthophis, Hoplocephalus, Notechis, Oxyuranus, Pseudechis, Pseudonaja and Tropidechis. However, even small species represent a potential for causing severe clinical envenoming.
Pycroft, Kyle +6 more
openaire +3 more sources
The venom gland transcriptome of the Desert Massasauga Rattlesnake (): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea) [PDF]
, 2007 BACKGROUND: Snake venoms are complex mixtures of pharmacologically active proteins and peptides which belong to a small number of superfamilies. Global cataloguing of the venom transcriptome facilitates the identification of new families of toxins as ...
Pahari, Susanta +2 more
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Role of accelerated segment switch in exons to alter targeting (ASSET) in the molecular evolution of snake venom proteins [PDF]
, 2009 BACKGROUND: Snake venom toxins evolve more rapidly than other proteins through accelerated changes in the protein coding regions. Previously we have shown that accelerated segment switch in exons to alter targeting (ASSET) might play an important role in
Robin Doley +2 more
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Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]
, 2011 Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L. +5 more
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, 2017 Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J +5 more
core +3 more sources