Results 51 to 60 of about 2,691 (214)

Toxinology of Venoms from Five Australian Lesser Known Elapid Snakes [PDF]

open access: yesBasic & Clinical Pharmacology & Toxicology, 2012
AbstractResearch into Australian elapid venoms has mainly focused on the seven genera of greatest clinical significance: Acanthophis, Hoplocephalus, Notechis, Oxyuranus, Pseudechis, Pseudonaja and Tropidechis. However, even small species represent a potential for causing severe clinical envenoming.
Pycroft, Kyle   +6 more
openaire   +3 more sources

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

open access: yes, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L.   +5 more
core   +2 more sources

Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades [PDF]

open access: yes, 2014
For over a century, venom samples from wild snakes have been collected and stored around the world. However, the quality of storage conditions for "vintage" venoms has rarely been assessed.
Addis   +63 more
core   +1 more source

Effect of Australian elapid venoms on blood coagulation: Australian Snakebite Project (ASP-17)

open access: hybridToxicon, 2012
Snake venoms contain toxins that activate the coagulation network and cause venom-induced consumption coagulopathy. A previously developed mathematical model of the coagulation network was refined and used to describe and predict the time course of changes in the coagulation factors following envenomation by Brown snake (Pseudonaja spp.), Tiger snake ...
Abhishek Gulati   +2 more
openalex   +3 more sources

Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

open access: yesScientific Reports, 2022
Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor dose efficacy and potency.
Stefanie K. Menzies   +9 more
doaj   +1 more source

The urgent need to develop novel strategies for the diagnosis and treatment of snakebites [PDF]

open access: yes, 2019
Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills over one hundred thousand people per year. However, many millions of survivors also suffer through disabilities and long-term health consequences.
Aagaard-Hansen   +39 more
core   +1 more source

Coral snake venoms: mode of action and pathophysiology of experimental envenomation

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1987
Coral snakes, the New World Elapidae, are included in the genera Micniroides and Micrurus. The genus Mlcrurus comprises nearly all coral snake species and those which are responsible for human snake-bite accidents.
Oswald Vital Brazil
doaj   +1 more source

Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib

open access: yesToxins, 2021
Bites from elapid snakes typically result in neurotoxic symptoms in snakebite victims. Neurotoxins are, therefore, often the focus of research relating to understanding the pathogenesis of elapid bites.
Taline D. Kazandjian   +7 more
doaj   +1 more source

Snakebite envenoming. [PDF]

open access: yes, 2017
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J   +5 more
core   +3 more sources

Evaluation of Antifungal Activity of Naja pallida and Naja mossambica Venoms against Three Candida Species

open access: yesToxins, 2020
In contrast to comprehensively investigated antibacterial activity of snake venoms, namely crude venoms and their selected components, little is known about antifungal properties of elapid snake venoms. In the present study, the proteome of two venoms of
Ewelina Kuna   +7 more
doaj   +1 more source

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