Results 51 to 60 of about 2,693 (220)

Coral snake venoms: mode of action and pathophysiology of experimental envenomation

Revista do Instituto de Medicina Tropical de São Paulo, 1987
Coral snakes, the New World Elapidae, are included in the genera Micniroides and Micrurus. The genus Mlcrurus comprises nearly all coral snake species and those which are responsible for human snake-bite accidents.
Oswald Vital Brazil
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Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

Scientific Reports, 2022
Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor dose efficacy and potency.
Stefanie K. Menzies, Charlotte A. Dawson, Edouard Crittenden, Rebecca J. Edge, Steven R. Hall, Jaffer Alsolaiss, Mark C. Wilkinson, Nicholas R. Casewell, Robert A. Harrison, Stuart Ainsworth   +9 more
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Haemotixic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise [PDF]

, 2017
Snake venoms are mixtures of numerous proteinacious components that exert diverse functional activities on a variety of physiological targets. Because the toxic constituents found in venom vary from species to species, snakebite victims can present with ...
Abubakar, Alirol, Alirol, Amiconi, Andrião-Escarso, Antonypillai, Arlinghaus, Arnold, Berling, Calvete, Calvete, Camargo, Casewell, Casewell, Casewell, Casewell, Casewell, Chakrabarty, Chippaux, Chippaux, Chippaux, Cousin, Deshpande, Durban, Earl, Escalante, Ferreira, Flight, Flight, Fox, Fry, Fry, Funk, Greene, Gutiérrez, Gutiérrez, Habib, Han, Harrison, Harrison, Harrison, Hutton, Illig, Isbister, Isbister, Isbister, Kasturiratne, Katkar, Kerkkamp, King, Kini, Lu, Lynch, Maduwage, Markland, Marrakchi, Marsh, Massey, McCleary, Modesto, Moll, Mosquera, Moura-da-Silva, Nowak, Oyama, Peerlinck, Phillips, Pirkle, Pla, Reza, Reza, Rivel, Rosing, Rucavado, Scarborough, Segura, Shimokawa, Siigur, Silva, Smith, Stocker, Stocker, Tan, Tan, Tan, Teixeira, Triplett, Vidal, Visser, Vonk, Vonk, Warrell, Warrell, Williams, Williams, Xu, Xu, Zhang   +97 more
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Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins [PDF]

Journal of Molecular Evolution, 2003
Animal venom components are of considerable interest to researchers across a wide variety of disciplines, including molecular biology, biochemistry, medicine, and evolutionary genetics. The three-finger family of snake venom peptides is a particularly interesting and biochemically complex group of venom peptides, because they are encoded by a large ...
Fry, B.G., Wüster, W., Kini, R.M., Brusic, V., Khan, A., Venkataraman, D., Rooney, A.P.   +6 more
openaire   +3 more sources

Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib

Toxins, 2021
Bites from elapid snakes typically result in neurotoxic symptoms in snakebite victims. Neurotoxins are, therefore, often the focus of research relating to understanding the pathogenesis of elapid bites.
Taline D. Kazandjian, Arif Arrahman, Kristina B. M. Still, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Mark C. Wilkinson, Jeroen Kool   +7 more
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The urgent need to develop novel strategies for the diagnosis and treatment of snakebites [PDF]

, 2019
Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills over one hundred thousand people per year. However, many millions of survivors also suffer through disabilities and long-term health consequences.
Aagaard-Hansen, Abbas, Bdolah, Bicknell, , Blaylock, Bouazza, Chippaux, CSL, Dhananjaya, Fry, Griffin, Harvey, Kalita, Kardong, Kardong, Kisiel, Kisiel, Layfield, , Litschka-Koen, Mackessy, Modahl, Omidfar, Ottesen, Patel, , Paul, Schetinger, Seth, Shah, Trim, , Vaiyapuri, Vaiyapuri, , Vallance, , Vijeth, Warrell, Warrell, Warrell, Wei, Williams, , Wüster, Zolfagharian   +39 more
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Impact of Naja nigricollis Venom on the Production of Methaemoglobin

Toxins, 2018
Snakebite envenomation is an affliction currently estimated to be killing upwards of 100,000 people annually. Snakebite is associated with a diverse pathophysiology due to the magnitude of variation in venom composition that is observed worldwide.
Harry F. Williams, Paul Hayter, Divyashree Ravishankar, Anthony Baines, Harry J. Layfield, Lorraine Croucher, Catherine Wark, Andrew B. Bicknell, Steven Trim, Sakthivel Vaiyapuri   +9 more
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Evaluation of Antifungal Activity of Naja pallida and Naja mossambica Venoms against Three Candida Species

Toxins, 2020
In contrast to comprehensively investigated antibacterial activity of snake venoms, namely crude venoms and their selected components, little is known about antifungal properties of elapid snake venoms. In the present study, the proteome of two venoms of
Ewelina Kuna, Aleksandra Bocian, Konrad K. Hus, Vladimir Petrilla, Monika Petrillova, Jaroslav Legath, Anna Lewinska, Maciej Wnuk   +7 more
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Inventing an arsenal: adaptive evolution and neofunctionalization of snake venom phospholipase A genes [PDF]

, 2007
Background Gene duplication followed by functional divergence has long been hypothesized to be the main source of molecular novelty. Convincing examples of neofunctionalization, however, remain rare.
Lynch Vincent J
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Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades [PDF]

, 2014
For over a century, venom samples from wild snakes have been collected and stored around the world. However, the quality of storage conditions for "vintage" venoms has rarely been assessed.
Addis, Addis, Ali, Alun Jones, Amanda Nouwens, Aung, Azimzadeh, Barnosky, Boehm, Bonnet, Brooks, Brust, Bryan Grieg Fry, Cagle, Casewell, Clémence Jesupret, Covacevich, Daryl C. Yang, Dirzo, Dolyce H.W. Low, Egen, Eivind A.B. Undheim, Essl, Fowler, Fry, Fry, Ivan Koludarov, Jessica Steuten, Jordan Debono, Kate Baumann, Kelly Winter, Kenneth D. Winkel, Larissa Kern, Laura Greisman, Mahdokht Jouiaei, McCleary, Mirtschin, Morrison, Munekiyo, Nadya Panagides, Nathan Dunstan, Nicholas R. Casewell, Nirmalan, Opdam, Palmer-Toy, Paul Monagle, Pearn, Righetti, Robyn Summerhayes, Russell, Saez, Sarah Rossi, Sarre, Schoettler, Sprung, Steuten, Syed Abid Ali, Timothy N.W. Jackson, Trookman, Vera Ignjatovic, Wayne C. Hodgson, Wickramaratna, Winkel, Zhang   +63 more
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