Results 51 to 60 of about 5,598 (174)
Calcium Electroporation of Equine Sarcoids
Sarcoids are common equine skin tumors where the risk of recurrence after treatment is high, and better treatment options are warranted. Calcium electroporation is a novel anti-cancer treatment where lethally high calcium concentrations are introduced ...
Stine K. Frandsen +3 more
doaj +1 more source
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
The neural interface is a critical factor in governing efficient and safe charge transfer between a stimulating electrode and biological tissue. The interface plays a crucial role in the efficacy of electric stimulation in chronic implants and both ...
Amr Al Abed +6 more
doaj +1 more source
Gene electrotransfer is an attractive method of non-viral gene delivery. However, the mechanism of DNA penetration across the plasma membrane is widely discussed.
Angela Tesse +2 more
doaj +1 more source
Purified ginseng adventitious root polysaccharides (GARP) improve insulin resistance by enhancing glucose and lipid metabolism and reducing oxidative stress. These beneficial effects are mediated, at least in part, through activation of the Nrf2/Keap1 signaling pathway in cellular and animal models.
Tian‐fu Yang +5 more
wiley +1 more source
ABSTRACT Objective To investigate the therapeutic efficacy and underlying molecular mechanisms of stromal vascular fraction gel (SVF‐gel) combined with ultra‐pulsed fractional CO2 laser (UFCL) in the treatment of depressed scars. Methods A rat model of depressed scars was established by full‐thickness excision of dorsal skin.
Lei Chen, Lingling Liu, Qunqun Jiang
wiley +1 more source
Electroporation is a technology that increases cell membrane permeability by the application of electric pulses. Electrochemotherapy (ECT), the best-known application of electroporation, is a very effective local treatment for tumors of any histology in ...
Felipe Maglietti +6 more
doaj +1 more source
This review summarizes recent advances in biosensing technologies for Alzheimer's disease, including immunosensors, aptasensors, and hybrid platforms. Emphasis is placed on both the incorporation of nanomaterials, which enhance electron transfer, biomolecule immobilization, and signal amplification, enabling femtomolar detection, and the role of ...
Denisa‐Nicoleta Voicila +2 more
wiley +1 more source
Electroporation—a transient electric-field-induced increase in cell membrane permeability—can be used to facilitate the delivery of anticancer drugs for antitumour electrochemotherapy.
Diana Navickaite +6 more
doaj +1 more source
LNA-based Oligonucleotide Electrotransfer for miRNA Inhibition [PDF]
Micro-RNAs (miRNAs) are small regulatory RNAs that play an important role in disease development and progression and therefore represent a potential new class of therapeutic targets. However, an effective and safe clinical approach for miRNA inhibition remains elusive, primarily due to the lack of effective delivery methods.
Orio, Julie +6 more
openaire +2 more sources

