Results 51 to 60 of about 5,729 (171)
ATF3 Promotes Solasonine‐Triggered Ferroptosis in Glioma Cells by Suppressing Glycolysis
CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.Solasonine inhibits glycolysis by increasing ATF3 expression, thereby increasing hydrogen peroxide levels, promoting ferritinophagy and lipid peroxidation, leading to ferroptosis. Furthermore, hydrogen peroxide activates endoplasmic reticulum stress, promoting ATF3 expression, and the whole process forms a positive feedback loop.
Mingbo Jia +8 more
wiley +1 more source
In Vivo Imaging of Far-red Fluorescent Proteins after DNA Electrotransfer to Muscle Tissue
Biological Procedures Online, 2009 DNA electrotransfer to muscle tissue yields long-term, high levels of gene expression; showing great promise for future gene therapy. We want to characterize the novel far-red fluorescent protein Katushka as a marker for gene expression using time domain
Eriksen Jens +2 more
doaj +3 more sources
Frontiers in Neuroscience, 2019 The neural interface is a critical factor in governing efficient and safe charge transfer between a stimulating electrode and biological tissue. The interface plays a crucial role in the efficacy of electric stimulation in chronic implants and both ...
Amr Al Abed +6 more
doaj +1 more source
Calcium Electroporation of Equine Sarcoids
Animals, 2020 Sarcoids are common equine skin tumors where the risk of recurrence after treatment is high, and better treatment options are warranted. Calcium electroporation is a novel anti-cancer treatment where lethally high calcium concentrations are introduced ...
Stine K. Frandsen +3 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.ABSTRACT Age‐related hearing loss (ARHL) is a degenerative change in the auditory system, but its underlying mechanism remains unclear. In this study, using RNA sequencing technology, we analysed the expression profiles of mRNAs in the cochlear tissues of ARHL‐susceptible C57BL/6J (C57) mice and relatively resistant CBA/CaJ (CBA) mice.
Chen Li +11 more
wiley +1 more source
Scientific Reports, 2021 Gene electrotransfer is an attractive method of non-viral gene delivery. However, the mechanism of DNA penetration across the plasma membrane is widely discussed.
Angela Tesse +2 more
doaj +1 more source
2‐Hydroxyethyl Methacrylate Increases MMP‐1 and MMP‐3 Production in Human Gingival Fibroblasts
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.HEMA induces the production of MMP‐1 and MMP‐3 in human gingival fibroblasts by activating the p38 MAPK, JNK, and Akt signaling pathways. ABSTRACT 2‐Hydroxyethyl methacrylate (HEMA), a monomer commonly used in dental resin materials, has been reported to leach from polymerized resins.
Risa Okamoto +6 more
wiley +1 more source
Molecular Plant Pathology, Volume 27, Issue 9, September 2026.The ApHSF–ApCtf1β2–ApCUT3 transcriptional cascade links fungal adaptation to host‐derived ROS with cuticle penetration during infection. ApHSF promotes ROS detoxification and activates ApCtf1β2, which induces ApCUT3 expression and cuticle degradation, thereby coordinating oxidative stress adaptation with host barrier penetration.
Peng Yan +6 more
wiley +1 more source
ELECTROTRANSFER OF CYTOKINE GENES FOR CANCER TREATMENT
CBU International Conference Proceedings, 2018 Gene electrotransfer, which designates the combination of gene transfer and electroporation, is a physical method for transfecting genes into cells and tissues. Many reports for the utilization of this techniques in animals confirmed that gene electrotransfer is a safe and efficient method.
Chopra, Sonam, Šatkauskas, Saulius
openaire +2 more sources
Vaccines, 2020 Electroporation is a technology that increases cell membrane permeability by the application of electric pulses. Electrochemotherapy (ECT), the best-known application of electroporation, is a very effective local treatment for tumors of any histology in ...
Felipe Maglietti +6 more
doaj +1 more source