Results 41 to 50 of about 5,598 (174)

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux   +5 more
wiley   +1 more source

Numerical study of gene electrotransfer efficiency based on electroporation volume and electrophoretic movement of plasmid DNA

open access: yesBioMedical Engineering OnLine, 2018
Background The efficiency of gene electrotransfer, an electroporation-based method for delivery of pDNA into target tissues, depends on several processes.
Tadeja Forjanič, Damijan Miklavčič
doaj   +1 more source

In Vivo and Ex Vivo Gene Electrotransfer in Ophthalmological Disorders

open access: yesBiomedicines, 2022
The aim of this document is to present an overview of gene electrotransfer in ophthalmological disorders. In order to ensure an adequate variety of the assessed studies, several electronic databases were considered and studies published between January ...
Roberta Fusco   +6 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1491-1500, August 2026.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

The Evidence of the Bystander Effect after Bleomycin Electrotransfer and Irreversible Electroporation

open access: yesMolecules, 2021
One of current applications of electroporation is electrochemotherapy and electroablation for local cancer treatment. Both of these electroporation modalities share some similarities with radiation therapy, one of which could be the bystander effect.
Paulius Ruzgys   +4 more
doaj   +1 more source

Calcium Electrotransfer for Termination of Transgene Expression in Muscle [PDF]

open access: yesHuman Gene Therapy, 2011
Gene electrotransfer is expanding in clinical use, thus we have searched for an emergency procedure to stop transgene expression in case of serious adverse events. Calcium is cytotoxic at high intracellular levels, so we tested effects of calcium electrotransfer on transgene expression in muscle.
Hojman, Pernille   +4 more
openaire   +3 more sources

Betaine Promotes Milk Protein Synthesis via Alleviating Oxidative Stress Caused by NEFA in Mammary Epithelial Cells of Dairy Cows

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Betaine alleviated NEFA‐induced oxidative stress, which served as a central mechanistic link between fatty liver and mammary dysfunction, and concurrently improved milk protein synthesis via regulation of the Nrf2‐JAK2/STAT5/mTOR axis. ABSTRACT Background Fatty liver is highly prevalent in dairy cows and poses a significant challenge to the dairy ...
Wenyan Yan   +6 more
wiley   +1 more source

Cytosolic DNA Sensor Upregulation Accompanies DNA Electrotransfer in B16.F10 Melanoma Cells

open access: yesMolecular Therapy: Nucleic Acids, 2016
In several preclinical tumor models, antitumor effects occur after intratumoral electroporation, also known as electrotransfer, of plasmid DNA devoid of a therapeutic gene.
Katarina Znidar   +3 more
doaj   +1 more source

GW9508‐Induced Activation of GPR40 in Thymic Epithelial Cells: A Therapeutic Strategy to Delay Thymic Aging

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
GW9508 activates GPR40 to trigger Ca2+ influx and AMPKα signaling, repressing ERK1/2‐MAPK cascade. This pathway alleviates thymic epithelial cell senescence and restores T cell production to counteract thymus aging. ABSTRACT Age‐associated thymic involution leads to a reduction of T‐cell production, which constitutes a primary factor in ...
Qingqing Li   +11 more
wiley   +1 more source

In Vivo Imaging of Far-red Fluorescent Proteins after DNA Electrotransfer to Muscle Tissue

open access: yesBiological Procedures Online, 2009
DNA electrotransfer to muscle tissue yields long-term, high levels of gene expression; showing great promise for future gene therapy. We want to characterize the novel far-red fluorescent protein Katushka as a marker for gene expression using time domain
Eriksen Jens   +2 more
doaj   +3 more sources

Home - About - Disclaimer - Privacy