Results 1 to 10 of about 1,311,231 (402)

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1993
Several newly generated mouse embryonic stem (ES) cell lines were tested for their ability to produce completely ES cell-derived mice at early passage numbers by ES cell tetraploid embryo aggregation.
A. Nagy, J. Rossant, R. Nagy, W. Abramow-Newerly, J. Roder   +4 more
semanticscholar   +2 more sources

Modeling mammalian gastrulation with embryonic stem cells [PDF]

arXiv, 2017
Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and molecular processes that shape the embryo.
Amita, Arnold, Azioune, Bauwens, Bedzhov, Ben-Haim, Bernardo, Blin, Bolouri, Chambers, Coucouvanis, Dunn, Engler, Etoc, Farin, Gjorevski, Green, Gurdon, Harrison, Heemskerk, Heemskerk, Horii, Lee, Lei, Li, Lippmann, Loh, Meinhardt, Meinhardt, Mendjan, Migeotte, Müller, Nakamura, Nallet-Staub, Nemashkalo, Nemashkalo, Nowotschin, Pagliuca, Peerani, Perea-Gomez, Przybyla, Qin, Ranga, Rosowski, Saka, Sasai, Schohl, Shao, Shao, Simunovic, Sorre, Sun, Tang, ten Berge, Teo, Tewary, Théry, Turing, Turner, Turner, van den Brink, Warmflash, Wilson, Xu, Yang, Yu   +65 more
arxiv   +3 more sources

Targeting of embryonic stem cells by peptide-conjugated quantum dots. [PDF]

PLoS ONE, 2010
Targeting stem cells holds great potential for studying the embryonic stem cell and development of stem cell-based regenerative medicine. Previous studies demonstrated that nanoparticles can serve as a robust platform for gene delivery, non-invasive cell
Shuai Lu, Xing Xu, Wenxiu Zhao, Weiwei Wu, Hang Yuan, Huaibin Shen, Changhua Zhou, Lin Song Li, Lan Ma   +8 more
doaj   +5 more sources

The King is Dead, Long Live the King: Entering A New Era of Stem Cell Research and Clinical Development [PDF]

Journal of Translational Medicine, 2011
In mid November the biopharma industry was shocked by the announcement from Geron that they were ending work on embryonic stem cell research and therapy.
Ichim Thomas, Riordan Neil H, Stroncek David F   +2 more
doaj   +4 more sources

Development and application of haploid embryonic stem cells [PDF]

Stem Cell Research & Therapy
Haploid cells are a kind of cells with only one set of chromosomes. Compared with traditional diploid cells, haploid cells have unique advantages in gene screening and drug-targeted therapy, due to their phenotype being equal to the genotype.
Hai-Song Wang, Xin-Rui Ma, Yi-Hong Guo
doaj   +2 more sources

Derivation of multipotent mesenchymal precursors from human embryonic stem cells. [PDF]

PLoS Medicine, 2005
BACKGROUND: Human embryonic stem cells provide access to the earliest stages of human development and may serve as a source of specialized cells for regenerative medicine.
Tiziano Barberi, Lucy M Willis, Nicholas D Socci, Lorenz Studer   +3 more
doaj   +7 more sources

Proteomes and signalling pathways of antler stem cells. [PDF]

PLoS ONE, 2012
As the only known example of complete organ regeneration in mammals, deer antler in the growing or velvet phase is of major interest in developmental biology.
Chunyi Li, Anne Harper, Jonathan Puddick, Wenying Wang, Chris McMahon   +4 more
doaj   +8 more sources

Embryonic Stem Cells: Introducing Exogenous Regulators into Embryonic Stem Cells [PDF]

, 2011
The application of embryonic stem (ES) cells to research and therapy has been a landmark development in science. Cell therapy using ES cells depends on the progress of the stable culture conditions and differentiation induction methods. ES cells were first obtained directly from inner cell masses (ICMs) of blastocysts by Evans and Kaufman (1981), and ...
Cheon, Yong-Pil
openaire   +6 more sources

Embryonic stem cells [PDF]

Cell Proliferation, 2004
Abstract.  Embryonic stem cells have huge potential in the field of tissue engineering and regenerative medicine as they hold the capacity to produce every type of cell and tissue in the body. In theory, the treatment of human disease could be revolutionized by the ability to generate any cell, tissue, or even organ, ‘on demand’ in the laboratory. This
Anne E. Bishop, Helen J. Rippon
openaire   +5 more sources

Inter-species Transplantation of Blastocysts between Medaka and Zebrafish

Bio-Protocol, 2021
Transplantation of blastocysts from a donor to a host blastula constitutes a powerful experimental tool to tackle major developmental biology questions. The technique is widely implemented in diverse biological models including teleost fish, where it is ...
Jana Fuhrmann, Jasmin Onistschenko, Lazaro Centanin   +2 more
doaj   +1 more source