Results 1 to 10 of about 506,868 (329)
Development and application of haploid embryonic stem cells [PDF]
Stem Cell Research & TherapyHaploid cells are a kind of cells with only one set of chromosomes. Compared with traditional diploid cells, haploid cells have unique advantages in gene screening and drug-targeted therapy, due to their phenotype being equal to the genotype.
Hai-Song Wang, Xin-Rui Ma, Yi-Hong Guo
doaj +2 more sources
An Opposite Effect of the CDK Inhibitor, p18INK4c on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells [PDF]
, 2012 Self-renewal is a feature common to both adult and embryonic stem (ES) cells, as well as tumor stem cells (TSCs). The cyclin-dependent kinase inhibitor, p18INK4c, is a known tumor suppressor that can inhibit self-renewal of tumor cells or adult stem ...
Cindy Tian +8 more
core +22 more sources
Cell Proliferation, 2004 Abstract. Embryonic stem cells have huge potential in the field of tissue engineering and regenerative medicine as they hold the capacity to produce every type of cell and tissue in the body. In theory, the treatment of human disease could be revolutionized by the ability to generate any cell, tissue, or even organ, ‘on demand’ in the laboratory. This
Anne E. Bishop, Helen J. Rippon
openaire +5 more sources
Inter-species Transplantation of Blastocysts between Medaka and Zebrafish
Bio-Protocol, 2021 Transplantation of blastocysts from a donor to a host blastula constitutes a powerful experimental tool to tackle major developmental biology questions. The technique is widely implemented in diverse biological models including teleost fish, where it is ...
Jana Fuhrmann +2 more
doaj +1 more source
The Journal of Pathology, 2002 AbstractThe capacity of embryonic stem cells for virtually unlimited self‐renewal and differentiation capacity has opened up the prospect of widespread applications in biomedical research and regenerative medicine. For the latter, the cells provide hope that it will be possible to overcome the problems of donor tissue shortage and also, by making the ...
Anne E. Bishop +2 more
openaire +3 more sources
Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]
, 2007 Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
C.H. Papadimitriou +8 more
core +4 more sources
Embryonic Stem Cells in Cattle [PDF]
Reproduction in Domestic Animals, 2008 ContentsBecause of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated.
Enrique J. Gómez +7 more
openaire +7 more sources
Embryonic Stem Cell Markers [PDF]
Molecules, 2012 Embryonic stem cell (ESC) markers are molecules specifically expressed in ES cells. Understanding of the functions of these markers is critical for characterization and elucidation for the mechanism of ESC pluripotent maintenance and self-renewal, therefore helping to accelerate the clinical application of ES cells.
Wenxiu Zhao +4 more
openaire +4 more sources
Frontiers in Endocrinology, 2022 BackgroundEctopic lipid deposition plays a promoting role in many chronic metabolic diseases. Abnormal adipogenic differentiation of mesenchymal stem cells (MSCs) is an important cause of lipid deposition in organs.
Jian Tang +14 more
doaj +1 more source
Chicken embryonic stem cells as a non‐mammalian embryonic stem cell model [PDF]
Development, Growth & Differentiation, 2010 Embryonic stem cells (ESCs) were isolated in the early 1980s from mouse and in the late 1990s from primate and human. These cells present the unique property of self‐renewal and the ability to generate differentiated progeny in all embryonic lineages both in vitro and in vivo.
Fabrice Lavial +2 more
openaire +6 more sources