Results 21 to 30 of about 1,375,365 (258)
Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells
Stem Cells International, 2016 Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development.
Gergo Kovacs +2 more
doaj +1 more source
Targeting of embryonic stem cells by peptide-conjugated quantum dots. [PDF]
PLoS ONE, 2010 Targeting stem cells holds great potential for studying the embryonic stem cell and development of stem cell-based regenerative medicine. Previous studies demonstrated that nanoparticles can serve as a robust platform for gene delivery, non-invasive cell
Shuai Lu +8 more
doaj +1 more source
Porcine OCT4 reporter system as a tool for monitoring pluripotency states
Journal of Animal Reproduction and Biotechnology, 2021 Pluripotent stem cells could self-renew and differentiate into various cells. In particular, porcine pluripotent stem cells are useful for preclinical therapy, transgenic animals, and agricultural usage. These stem cells have naïve and primed pluripotent
Seung-Hun Kim, Chang-Kyu Lee
doaj +1 more source
SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells
Nature Communications, 2019 Endogenous retroviruses (ERVs) can confer benefits to their host but present a threat to genome integrity if not regulated correctly. Here we identify the SWI/SNF-like remodeler SMARCAD1 as a key factor in the control of ERVs in embryonic stem cells ...
Parysatis Sachs +8 more
semanticscholar +1 more source
Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types. [PDF]
, 2017 Many subtypes of cortical interneurons (CINs) are found in adult mouse cortices, but the mechanism generating their diversity remains elusive. We performed single-cell RNA sequencing on the mouse embryonic medial ganglionic eminence (MGE), the major ...
Chen, Ying-Jiun J +7 more
core +1 more source
Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells [PDF]
, 2013 Pluripotent stem cells, both embryonic stem cells and induced pluripotent stem cells, are undifferentiated cells that can self-renew and potentially differentiate into all hematopoietic lineages, such as hematopoietic stem cells (HSCs), hematopoietic ...
Inoue-Yokoo, Tomoko +4 more
core +1 more source
Stem Cell Research, 2019 We describe the generation and characterization of hiPSC lines of one type 1-Gaucher disease patient with Parkinson's disease and two unrelated Parkinson's disease patients heterozygous for GBA mutations.
Fabiano A. Tofoli +3 more
doaj +1 more source
Stem Cell Research, 2019 We describe generation of human induced pluripotent stem cell (hiPSC) lines of three unrelated idiopathic late onset Parkinson disease patients and two healthy controls above 60 years of age without neurological diseases nor Ashkenazi ancestry.
Fabiano de Araújo Tofoli +3 more
doaj +1 more source
A Sweet Potion to Put Embryonic Stem Cells to Sleep
The Scientific World Journal, 2009 Human embryonic stem cells (hESCs) are rapidly revolutionizing the areas of drug screening and therapy. In view of their applications and high operational costs at global multicentric setups, the ability to store and transport hESCs and derivatives under
Kaushik D. Deb
doaj +1 more source
Stem Cells from a Biological Perspective in Animals: A Review [PDF]
, 2017 Cells are the smallest living units of living system. Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide to produce more stem cells.
Jain, A. (Archana) +2 more
core +1 more source