Results 21 to 30 of about 1,367,138 (398)

Direct comparison of distinct naive pluripotent states in human embryonic stem cells [PDF]

open access: yes, 2017
Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed pluripotent state.
Chuva de Sousa Lopes, Susana Marina   +18 more
core   +1 more source

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

open access: yesScience, 2020
Trunk formation in a dish Building mammalian embryos from self-organizing stem cells in culture would accelerate the investigation of morphogenetic and differentiation processes that shape the body plan. Veenvliet et al.
Jesse V. Veenvliet   +15 more
semanticscholar   +1 more source

GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]

open access: yes, 2013
Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Andras Dinnyes   +6 more
core   +1 more source

Enhanced differentiation of human embryonic stem cells towards definitive endoderm on ultrahigh aspect ratio nanopillars [PDF]

open access: yes, 2015
Differentiation of human embryonic stem cells is widely studied as a potential unlimited source for cell replacement therapy to treat degenerative diseases such as diabetes.
Dufva, Martin   +6 more
core   +2 more sources

Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]

open access: yes, 2011
Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz   +9 more
core   +1 more source

Introducing embryonic stem cells [PDF]

open access: yesCurrent Biology, 2001
The editors of Current Biology welcome correspondence on any article in the journal, but reserve the right to reduce the length of any letter to be published. All Correspondence containing data or scientific argument will be refereed. Items for publication should either be submitted typed, double-spaced to: The Editor, Current Biology, Elsevier Science
openaire   +3 more sources

Reprogramming Malignant Cancer Cells toward a Benign Phenotype following Exposure to Human Embryonic Stem Cell Microenvironment. [PDF]

open access: yesPLoS ONE, 2017
The embryonic microenvironment is well known to be non-permissive for tumor development because early developmental signals naturally suppress the expression of proto-oncogenes.
Shufeng Zhou   +4 more
doaj   +1 more source

Loss of stem cell regenerative capacity within aged niches. [PDF]

open access: yes, 2007
This work uncovers novel mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans and affect both embryonic and adult stem cells.
Carlson, Morgan, CONBOY, Irina M
core   +3 more sources

Embryonic stem cell proteomics

open access: yesExpert Review of Proteomics, 2006
Human embryonic stem cells potentially represent an unlimited source of cells and tissues for regenerative medicine. Understanding signaling events that drive proliferation and specialization of these cells into various differentiated derivatives is of utmost importance for controlling their behavior in vitro. Major progress has been made in unraveling
van Hoof, D.   +3 more
openaire   +5 more sources

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