Direct comparison of distinct naive pluripotent states in human embryonic stem cells [PDF]
, 2017 Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed pluripotent state.
Chuva de Sousa Lopes, Susana Marina +18 more
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GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]
, 2013 Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Andras Dinnyes +6 more
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Enhanced differentiation of human embryonic stem cells towards definitive endoderm on ultrahigh aspect ratio nanopillars [PDF]
, 2015 Differentiation of human embryonic stem cells is widely studied as a potential unlimited source for cell replacement therapy to treat degenerative diseases such as diabetes.
Dufva, Martin +6 more
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Embryonic Stem Cells in Cattle [PDF]
Reproduction in Domestic Animals, 2008 ContentsBecause of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated.
Munoz, M +5 more
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Reprogramming Malignant Cancer Cells toward a Benign Phenotype following Exposure to Human Embryonic Stem Cell Microenvironment. [PDF]
PLoS ONE, 2017 The embryonic microenvironment is well known to be non-permissive for tumor development because early developmental signals naturally suppress the expression of proto-oncogenes.
Shufeng Zhou +4 more
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Introducing embryonic stem cells [PDF]
Current Biology, 2001 The editors of Current Biology welcome correspondence on any article in the journal, but reserve the right to reduce the length of any letter to be published. All Correspondence containing data or scientific argument will be refereed. Items for publication should either be submitted typed, double-spaced to: The Editor, Current Biology, Elsevier Science
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Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells
Stem Cells International, 2016 Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development.
Gergo Kovacs +2 more
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Porcine OCT4 reporter system as a tool for monitoring pluripotency states
Journal of Animal Reproduction and Biotechnology, 2021 Pluripotent stem cells could self-renew and differentiate into various cells. In particular, porcine pluripotent stem cells are useful for preclinical therapy, transgenic animals, and agricultural usage. These stem cells have naïve and primed pluripotent
Seung-Hun Kim, Chang-Kyu Lee
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Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]
, 2011 Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz +9 more
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Targeting of embryonic stem cells by peptide-conjugated quantum dots. [PDF]
PLoS ONE, 2010 Targeting stem cells holds great potential for studying the embryonic stem cell and development of stem cell-based regenerative medicine. Previous studies demonstrated that nanoparticles can serve as a robust platform for gene delivery, non-invasive cell
Shuai Lu +8 more
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