Results 51 to 60 of about 3,221,112 (244)
Enantioselective Total Synthesis of (+)‐Obtusenyne. [PDF]
ChemInform, 2003 A total synthesis of the laurencia metabolite (+)-obtusenyne has been completed. The key steps include a Sharpless kinetic resolution and an asymmetric glycolate alkylation to establish the stereogenic centers adjacent to the ether linkage and a ring-closing metathesis reaction to construct the nine-membered ether without the aid of a cyclic ...
Mark T. Powell, Michael T. Crimmins
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Organocatalyst-mediated five-pot synthesis of (–)-quinine
Nature Communications, 2022 Syntheses of quinine have fascinated organic chemists for over a hundred years. Here, the authors developed an organocatalyst-mediated pot-economical enantioselective total synthesis using five reaction vessels.
Takahiro Terunuma, Yujiro Hayashi
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Enantioselective Total Synthesis of (+)-Jasplakinolide [PDF]
Organic Letters, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Arun K. Ghosh and, Deuk Kyu Moon
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iScience, 2019 Summary: The direct functionalization of C(sp3)-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion.
Cheng-Yu Wang +5 more
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Journal of the American Chemical Society, 2018 While interest in the synthetic chemistry of radical cations continues to grow, controlling enantioselectivity in the reactions of these intermediates remains a challenge. Based on recent insights into the oxidation of tryptophan in enzymatic systems, we
Emily C. Gentry +4 more
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Enantioselective formal synthesis of (+)-madangamine A
Chemical Communications, 2019 A formal synthesis of (+)-madangamine A from phenylglycinol-derived lactam 1, involving the final closure of the peripheral rings from the skipped polyunsaturated diazatricyclic derivative 19, is reported.
Celeste Are +3 more
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Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes
Nature Communications, 2019 Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non ...
Shihua Song +3 more
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Enantioselective Total Synthesis of (‐)‐Xialenon A.
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Hodgson, D, Galano, J, Christlieb, M
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Thioketone-directed rhodium(I) catalyzed enantioselective C-H bond arylation of ferrocenes
Nature Communications, 2019 The development of straightforward methods for the synthesis of planar chiral ferrocenes remains highly challenging. Here, the authors report a rhodium(I)/phosphonate-catalyzed thioketone-directed enantioselective C-H bond arylation reaction for the ...
Zhong-Jian Cai +4 more
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Enantioselective Synthesis of Nonracemic Geminal Silylboronates by Pt-Catalyzed Hydrosilylation.
ACS Catalysis, 2018 A Pt-catalyzed enantioselective hydrosilylation of alkenylboronates is described. This reaction occurs with high regio- and enantioselectivity, providing a convenient route to chiral non-racemic geminal silylboronates. These compounds are useful reagents
A. Szymaniak +3 more
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