Results 151 to 160 of about 39,817 (294)
Angewandte Chemie, EarlyView.The total synthesis of isodaphlongamine H was accomplished by a lactam strategy. This strategy started with alkylation and N‐oxidation of a readily available chiral lactam. For the key functionalization of the amide carbonyl, an iridium‐catalyzed reductive [3 + 2] cycloaddition of the N‐hydroxylactam afforded the tricyclic isoxazolidine, which was ...
Sora Iwamoto +15 more
wiley +2 more sources
Enantioselective Hydrogenation of Ketopantolactone
Journal of Catalysis, 1997 The enantioselective hydrogenation of ketopantolactone toR-(−)-pantolactone was investigated on 5 wt% Pt/Al2O3chirally modified with cinchonidine. The influence of catalyst pretreatment conditions, hydrogen pressure, temperature, solvent polarity, and catalyst, reactant, and modifier concentrations was studied in a slurry reactor.
Schürch, Markus +4 more
openaire +3 more sources
Angewandte Chemie, EarlyView.A highly enantioselective iridium‐catalyzed hydroarylation of allene‐tethered pyrroles and indoles that provides access to relevant heterocyclic systems bearing vinyl‐substituted 3ry or 4ry stereocenters is reported. Its synthetic potential was exemplified with a very short, highly enantioselective formal synthesis of (+)‐Rhazinilam, whereas DFT ...
Andrés Arribas +4 more
wiley +2 more sources
Nickel‐Catalyzed Suzuki–Miyaura Cross‐Coupling Reaction of Aliphatic Alcohol Derivatives
Angewandte Chemie, EarlyView.A nickel‐catalyzed Suzuki–Miyaura coupling reaction of aliphatic mesylates is reported. This reaction provides a strategy for late‐stage functionalization of bioactive compounds that have high F(sp3). Preliminary mechanistic experiments confirm a stereoablative reaction outcome, consistent with alkyl radical intermediates.
Chloe D. Wong +3 more
wiley +2 more sources
Marine DrugsThis study explores the reasons behind the variations in the enantioselectivity of the sulfoxidation of methyl phenyl sulfide by marine-derived vanadium-dependent haloperoxidases (VHPOs). Twelve new VHPOs of marine organisms were overexpressed, purified,
Yun-Han Zhang +4 more
doaj +1 more source
AgricultureFungicides play a role in managing plant diseases but raise concerns about environmental impact, emphasizing the need to understand and minimize their effects on non-target ecosystems. Flutriafol is a fungicide used to combat fungal diseases in crops. It
Diana-Larisa Roman +4 more
doaj +1 more source
Design and Synthesis of Oxazoline-Based Scaffolds for Hybrid Lewis Acid/Lewis Base Catalysis of Carbon–Carbon Bond Formation [PDF]
, 2016 A new class of hybrid Lewis acid/Lewis base catalysts has been designed and prepared with an initial objective of promoting stereoselective direct aldol reactions.
Benoit, Adam R. +6 more
core +1 more source
Enantiodiscrimination through Oriented Attachment: Formation of Homochiral Crystal Aggregates from a Racemic System [PDF]
arXiv, 2012 We show that D- and L-enantiomorphous crystals of NaBrO3 in equilibrium with the corresponding solution, self-aggregate leading to large crystal assemblies. Surprisingly, crystal-to-crystal interaction is not a random process and takes place with nearly complete enantioselection (chiral recognition) thereby providing homochiral aggregates.
arxiv
Properties of epoxide hydrolase from the yeast Rhodotorula glutinis [PDF]
Epoxide hydrolases are ubiquitous enzymes that can be found in nearly all living organisms. Some of the enzymes play an important role in detoxifying xenobiotic and metabolic compounds.
Ariës-Kronenburg, N.A.E.
core +1 more source
Enantioselectivity on Surfaces [PDF]
, 2008 David M. Rampulla, Andrew J. Gellman
openaire +2 more sources