Results 61 to 70 of about 46,188 (225)
Cannabinoid ligands, receptors and enzymes: Pharmacological tools and therapeutic potential
Brain and Neuroscience Advances, 2018 Endocannabinoids have been identified to have roles in numerous physiological and pathological processes. Largely due to the association of the effects of Cannabis administration on mental states, the CNS impact of the endocannabinoid system has been the
Wafa Hourani, Stephen P. H. Alexander
doaj +1 more source
Анналы клинической и экспериментальной неврологии, 2017 Reviewed are modern concepts concerning physiological role and mechanisms of brain functioning of the endocannabinoid signaling system comprising cannabinoid receptors, endocannabinoids and proteins participating in their synthesis, transport and ...
V. P. Barkhatova
doaj +1 more source
Molecules, 2022 Since the discovery of α-synuclein as the major component in Lewy bodies, research into this protein in the context of Parkinson’s disease pathology has been exponential.
Rachel Kelly +5 more
doaj +1 more source
Differentiating Nonsuicidal Self‐Injury (NSSI) From Suicide Attempts in Adolescents: A Pilot Study
Medicine Bulletin, EarlyView.ABSTRACT Background Differentiating between nonsuicidal self‐injury (NSSI) and suicide attempts (SA) in adolescents is crucial due to distinct underlying motivations, treatment needs, and potential outcomes associated with each behavior.
María Posada‐Ayala +9 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani +3 more
wiley +1 more source
Multiple Roles of Cannabinoids in the Olfactory System
Brain SciencesThe endocannabinoid system is a ubiquitous neuromodulatory network that links internal physiological state to neural circuit function across the brain. While its roles in memory, reward, pain, and motor control are well established, its contribution to ...
Thomas Heinbockel, Edward A. Brown
doaj +1 more source
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Non-opioid Analgesics and the Endocannabinoid System
Balkan Medical Journal, 2020 Non-steroidal anti-inflammatory drugs produce antinociceptive effects mainly through peripheral cyclooxygenase inhibition. In opposition to the classical non-steroidal anti-inflammatory drugs, paracetamol and dipyrone exert weak anti-inflammatory ...
Ruhan Deniz Topuz +3 more
doaj +1 more source
Cannabinoid Signalling in Immune–Reproductive Crosstalk during Human Pregnancy
Biomedicines, 2021 Despite the intricate involvement of the endocannabinoid system in various physiological processes, it remains one of the most under-studied biological systems of the human body.
Harmeet Gurm +2 more
doaj +1 more source
The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl. [PDF]
Dev DynAbstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Tolentino M +3 more
europepmc +2 more sources