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Endocannabinoid system and anticancer properties of cannabinoids [PDF]
, 2016 Cannabinoids impact human body by binding to cannabinoids receptors (CB1 and CB2). The two main phytocannabinoids are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
Nowak, Agnieszka +3 more
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Endocannabinoids and Schizophrenia
Pharmaceuticals, 2010 The endocannabinoids anandamide and 2-arachydonoylglycerol (2-AG) are lipids naturally derived from membrane precursors which bind cannabinoid receptors (CB1, CB2). This endocannabinoid system is disturbed in schizophrenia.
Stéphane Potvin +3 more
doaj +1 more source
2-arachidonoylglycerol metabolism is differently modulated by oligomeric and fibrillar conformations of amyloid beta in synaptic terminals [PDF]
, 2017 Alzheimer´s disease (AD) is the most prevalent disorder of senile dementia mainly characterized by amyloid-beta peptide (Aβ) deposits in the brain. Cannabinoids are relevant to AD as they exert several beneficial effects in many models of this disease ...
Gaveglio, Virginia Lucía +3 more
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PLoS ONE, 2014 BackgroundEndocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females.
Fernando Fernández-Aranda +19 more
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Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response
Frontiers in Immunology, 2021 Endocannabinoids are endogenous ligands of cannabinoid receptors and activation of these receptors has strong physiological and pathological significance.
Qiongqiong Zhou +7 more
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The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers
International Journal of Endocrinology, 2013 The “endocannabinoid system (ECS)” comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport ...
Thangesweran Ayakannu +4 more
doaj +1 more source
Cannabinoids, Endocannabinoids and Sleep
Frontiers in Molecular Neuroscience, 2020 Sleep is a vital function of the nervous system that contributes to brain and bodily homeostasis, energy levels, cognitive ability, and other key functions of a variety of organisms. Dysfunctional sleep induces neural problems and is a key part of almost
Andrew J. Kesner +2 more
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A co-ultramicronized palmitoylethanolamide/luteolin composite mitigates clinical score and disease-relevant molecular markers in a mouse model of experimental autoimmune encephalomyelitis [PDF]
, 2019 Background: Persistent and/or recurrent inflammatory processes are the main factor leading to multiple sclerosis (MS) lesions. The composite ultramicronized palmitoylethanolamide, an endogenous N-acylethanolamine, combined with the flavonoid luteolin ...
Barbierato, M. +5 more
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Molecules, 2019 The hippocampus is thought to encode information by altering synaptic strength via synaptic plasticity. Some forms of synaptic plasticity are induced by lipid-based endocannabinoid signaling molecules that act on cannabinoid receptors (CB1 ...
Lindsey N. Friend +8 more
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Scientific Reports, 2021 Endocannabinoids, particularly anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are instrumental in regulating energy homeostasis and stress response.
Isabel van Ackern +4 more
doaj +1 more source