Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx [PDF]
Malaria Journal, 2017 Background Plasmodium falciparum-infected erythrocytes sequester in the microcirculation due to interaction between surface-expressed parasite proteins and endothelial receptors.
Casper Hempel +3 more
doaj +5 more sources
Lectin Staining of Microvascular Glycocalyx in Microfluidic Cancer Cell Extravasation Assays
Life, 2021 The endothelial glycocalyx forms the inner-most lining of human microvasculature. It ensures the physiological function of blood vessels and plays a crucial role in the occurrence and progression of microvascular diseases.
Sebastian Beyer +5 more
doaj +1 more source
BMC Nephrology, 2021 Background Damage to the endothelial glycocalyx is an early indicator of vascular damage and a potential marker of endothelial dysfunction. This study aimed to assess the relationship between markers of glycocalyx damage, endothelial dysfunction, and ...
Hui Liew +3 more
doaj +1 more source
Endothelial Glycocalyx Degradation in Critical Illness and Injury
Frontiers in Medicine, 2022 The endothelial glycocalyx is a gel-like layer on the luminal side of blood vessels that is composed of glycosaminoglycans and the proteins that tether them to the plasma membrane.
Eric K. Patterson +7 more
doaj +1 more source
The Structure and Function of the Glycocalyx and Its Connection With Blood-Brain Barrier
Frontiers in Cellular Neuroscience, 2021 The vascular endothelial glycocalyx is a dense, bush-like structure that is synthesized and secreted by endothelial cells and evenly distributed on the surface of vascular endothelial cells.
Jing Jin +6 more
doaj +1 more source
Reactive Oxygen Species Modulate the Barrier Function of the Human Glomerular Endothelial Glycocalyx [PDF]
, 2013 Reactive oxygen species (ROS) play a key role in the pathogenesis of proteinuria in glomerular diseases like diabetic nephropathy. Glomerular endothelial cell (GEnC) glycocalyx covers the luminal aspect of the glomerular capillary wall and makes an ...
Dasgupta, I +9 more
core +14 more sources
Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]
, 2008 A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Becker, Bernhard F. +6 more
core +1 more source
Critical Care, 2017 Background Sugar-protein glycocalyx coats healthy endothelium, but its ultrastructure is not well described. Our aim was to determine the three-dimensional ultrastructure of capillary endothelial glycocalyx in the heart, kidney, and liver, where ...
Hideshi Okada +20 more
doaj +1 more source
Glycocalyx Degradation in Retinal and Choroidal Capillary Endothelium in Rats with Diabetes and Hypertension [PDF]
, 2010 Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear.
Kumase, Fumiaki +5 more
core +1 more source
Initial interaction of citrate-coated iron oxide nanoparticles with the glycocalyx of THP-1 monocytes assessed by real-time magnetic particle spectroscopy and electron microscopy [PDF]
, 2020 Interaction with biological material can alter physicochemical parameters of magnetic nanoparticles and might thereby change their magnetic behavior with potentially important implications for various nanoparticle applications.
Ludwig, Antje +7 more
core +1 more source