Results 31 to 40 of about 571,172 (234)
A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx. [PDF]
PLoS ONE, 2010 BACKGROUND: Some low molecular weight heparins (LMWHs) prolong survival of cancer patients and inhibit experimental metastasis. The underlying mechanisms are still not clear but it has been suggested that LMWHs (at least in part) limit metastasis by ...
Geerte L Van Sluis +5 more
doaj +1 more source
PLoS ONE, 2023 Background Sepsis-associated encephalopathy (SAE) is characterized by a diffuse cerebral dysfunction that accompanies sepsis in the absence of direct central nervous system infection.
Sheon Baby +4 more
semanticscholar +1 more source
Lectin Staining of Microvascular Glycocalyx in Microfluidic Cancer Cell Extravasation Assays
Life, 2021 The endothelial glycocalyx forms the inner-most lining of human microvasculature. It ensures the physiological function of blood vessels and plays a crucial role in the occurrence and progression of microvascular diseases.
Sebastian Beyer +5 more
doaj +1 more source
Blood Coagulation and Fibrinolysis, 2023 Disseminated intravascular coagulation (DIC) is a complex disorder characterized by widespread activation of blood clotting mechanisms throughout the body. Understanding the role of vascular endothelial glycocalyx in the pathogenesis and treatment of DIC
Jingjing Cao, Yi Chen
semanticscholar +1 more source
Shock, 2023 Objectives: This study investigated the role and potential involvement of pulmonary vascular glycocalyx degradation in acute lung injury in rats with severe heatstroke (HS).
Jingjing Cao +4 more
semanticscholar +1 more source
The Structure and Function of the Glycocalyx and Its Connection With Blood-Brain Barrier
Frontiers in Cellular Neuroscience, 2021 The vascular endothelial glycocalyx is a dense, bush-like structure that is synthesized and secreted by endothelial cells and evenly distributed on the surface of vascular endothelial cells.
Jing Jin +6 more
doaj +1 more source
Comprehensive Physiology, 2022 The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is primarily conformed of glycoproteins and proteoglycans, which provide communication, electrostatic charge, ionic buffering, permeability, and mechanosensation ...
Christopher A. Foote +7 more
semanticscholar +1 more source
Reactive Oxygen Species Modulate the Barrier Function of the Human Glomerular Endothelial Glycocalyx [PDF]
, 2013 Reactive oxygen species (ROS) play a key role in the pathogenesis of proteinuria in glomerular diseases like diabetic nephropathy. Glomerular endothelial cell (GEnC) glycocalyx covers the luminal aspect of the glomerular capillary wall and makes an ...
Dasgupta, I +9 more
core +14 more sources
Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]
, 2008 A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Becker, Bernhard F. +6 more
core +1 more source
Vascular Endothelial Glycocalyx Damage and Potential Targeted Therapy in COVID-19
Cells, 2022 COVID-19 is a highly infectious respiratory disease caused by a new coronavirus known as SARS-CoV-2. COVID-19 is characterized by progressive respiratory failure resulting from diffuse alveolar damage, inflammatory infiltrates, endotheliitis, and ...
Duoduo Zha, M. Fu, Yisong Qian
semanticscholar +1 more source