Results 51 to 60 of about 571,172 (234)

Endothelial glycocalyx degradation in multisystem inflammatory syndrome in children related to COVID-19

Journal of molecular medicine, 2022
Multisystem inflammatory syndrome in children (MIS-C) represents a rare but severe complication of severe acute respiratory syndrome coronavirus 2 infection affecting children that can lead to myocardial injury and shock. Vascular endothelial dysfunction
N. Veraldi, R. Vivès, Géraldine Blanchard-Rohner, A. L'Huillier, N. Wagner, M. Rohr, M. Beghetti, A. D. de Agostini, S. Grazioli   +8 more
semanticscholar   +1 more source

Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]

, 2010
Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F., Bruegger, Dirk, Chappell, Daniel, Conzen, Peter, Jacob, Matthias, Kaczmarek, Ingo, Rehm, Markus, Stoeckelhuber, Mechthild, Welsch, Ulrich   +8 more
core   +1 more source

Endothelial glycocalyx is damaged in diabetic cardiomyopathy: angiopoietin 1 restores glycocalyx and improves diastolic function in mice

Diabetologia, 2022
Diabetic cardiomyopathy (DCM) is a serious and under-recognised complication of diabetes. The first sign is diastolic dysfunction, which progresses to heart failure.
Yan Qiu, Stanley Buffonge, R. Ramnath, Sophie Jenner, S. Fawaz, K. Arkill, Chris Neal, Paul Verkade, Stephen J. White, M. Hezzell, Andrew H. J. Salmon, M.-Saadeh Suleiman, Gavin I. Welsh, R. Foster, P. Madeddu, S. Satchell   +15 more
semanticscholar   +1 more source

Pro-atherosclerotic disturbed flow disrupts caveolin-1 expression, localization, and function via glycocalyx degradation

Journal of Translational Medicine, 2018
Background Endothelial-dependent atherosclerosis develops in a non-random pattern in regions of vessel bending and bifurcations, where blood flow exhibits disturbed flow (DF) patterns.
Ian C. Harding, Ronodeep Mitra, Solomon A. Mensah, Ira M. Herman, Eno E. Ebong   +4 more
doaj   +1 more source

Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis

Respiratory Research, 2022
Highlights It is the first time to prove the confirm the endothelial glycocalyx impairment in COPD. FGF10 attenuates the development of emphysema and the shedding of glycocalyx induced by CSE in vivo.
Tian Jiang, Weiping Hu, Shaoyuan Zhang, Changhao Ren, Siyun Lin, Zhenyu Zhou, Hao Wu, Jun Yin, Lijie Tan   +8 more
doaj   +1 more source

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function [PDF]

, 2017
The endothelial glycocalyx forms a continuous coat over the luminal surface of all vessels, and regulates multiple vascular functions. The contribution of individual components of the endothelial glycocalyx to one critical vascular function ...
Aamelfot, Adamson, Adamson, Adamson, Adamson, Adembri, Arkill, Bai, Baldwin, Barker, Bates, Bates, Bingaman, Born, Cai, Cassidy, Chappell, Cioffi, Cuniberti, Curry, Curry, Curry, Curry, Curry, Curry, Curry, Damiano, Dekan, Florian, Fu, Fu, Gao, Gelberg, Geyer, Gorog, Gretz, Haraldsson, Haraldsson, Hu, Huxley, Huxley, Jeansson, Jeansson, Jeansson, Kendall, Kumagai, Lee, Levick, Mason, Michel, Michel, Michel, Nassimizadeh, Oltean, Pahakis, Peti-Peterdi, Pries, Sakarya, Salmon, Salmon, Salmon, Schindelin, Singh, Squire, Tarbell, Tarbell, Tarbell, Tatsuzuki, Vargas, Varki, Weinbaum, Weinbaum, Yen, Zeng   +73 more
core   +3 more sources

Modeling the Endothelial Glycocalyx Layer in the Human Conventional Aqueous Outflow Pathway

Cells, 2022
A layer of proteoglycans and glycoproteins known as glycocalyx covers the surface of the trabecular meshwork (TM), juxtacanalicular tissue (JCT), and Schlemm’s canal (SC) inner wall of the conventional aqueous outflow pathway in the eye.
A. Karimi, M. Halabian, R. Razaghi, J. Downs, M. Kelley, T. Acott   +5 more
semanticscholar   +1 more source

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx [PDF]

, 2020
Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium.
Hegermann, Jan, Kuebler, Wolfgang M., Lopez-Rodriguez, Elena, Matuszak, Jasmin, Nouailles, Geraldine, Ochs, Matthias, Simmons, Szandor, Timm, Sara, Witzenrath, Martin   +8 more
core   +1 more source

The Glomerular Endothelium Restricts Albumin Filtration

Frontiers in Medicine, 2021
Inflammatory activation and/or dysfunction of the glomerular endothelium triggers proteinuria in many systemic and localized vascular disorders. Among them are the thrombotic microangiopathies, many forms of glomerulonephritis, and acute inflammatory ...
Barbara J. Ballermann, Jenny Nyström, Börje Haraldsson   +2 more
doaj   +1 more source

Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease [PDF]

, 2016
The past decade has resulted in multiple new findings of potential proteomic biomarkers of diabetic kidney disease (DKD). Many of these biomarkers reflect an important role in the (patho)physiology and biological processes of DKD.
Heerspink, Hiddo J.L., Mischak, Harald, Pena, Michelle J.   +2 more
core   +7 more sources