Results 51 to 60 of about 47,074 (275)

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

Annals of Neurology, EarlyView.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim, Manyoel Lim, Thiago D. Nascimento, Frank Porreca, Robert A. Koeppe, Nouchine Hadjikhani, Alexandre F. DaSilva   +6 more
wiley   +1 more source

Effects of Restraint Stress on Circulating Corticosterone and Met Enkephalin in Chickens: Induction of Shifts in Insulin Secretion and Carbohydrate Metabolism. [PDF]

Animals (Basel)
This study examined the effects of acute restraint stress in the presence or absence of naltrexone on the circulating concentrations of insulin, glucose, Met-enkephalin and corticosterone in 14-week-old chickens [design: 2 sex × 2 stress/non-stress × 2 +/
Scanes CG, Pierzchała-Koziec K, Gajewska A.   +2 more
europepmc   +2 more sources

Comparative Study of Multicanonical and Simulated Annealing Algorithms in the Protein Folding Problem [PDF]

, 1994
We compare a few variants of the recently proposed multicanonical method with the well known simulated annealing for the effectiveness in search of the energy global minimum of a biomolecular system. For this we study in detail Met-enkephalin, one of the
Affinger, Berg, Berg, Berg, Berg, Berg, Berg, Brünger, Brünger, Celik, Chou, Ferrenberg, Ferrenberg, Fukugita, Garrett, Goodsell, Hansmann, Hansmann, Kawai, Kawai, Kirkpatrick, Levitt, Li, Metropolis, Momany, Nakai, Nakazawa, Nilges, Némethy, Okamoto, Okamoto, Okamoto, Okamoto, Okamoto, Shakhnovich, Sipple, Ulrich H.E. Hansmann, von Freyberg, Wilson, Wilson, Wilson, Yuko Okamoto   +41 more
core   +3 more sources

Delta Opioid Receptors and Enkephalinergic Signaling within Locus Coeruleus Promote Stress Resilience

Brain Sciences, 2022
The noradrenergic nucleus locus coeruleus is a key component of the stress circuitry of the brain. During stress, the neuropeptide corticotropin-releasing factor (CRF) is secreted onto LC, increasing LC output and norepinephrine concentration in the ...
John A. Tkaczynski, Olga Borodovitsyna, Daniel J. Chandler   +2 more
doaj   +1 more source

Generalized-ensemble Monte carlo method for systems with rough energy landscape

, 1997
We present a novel Monte Carlo algorithm which enhances equilibrization of low-temperature simulations and allows sampling of configurations over a large range of energies.
A. M. Ferrenberg, A. P. Lyubartsev, B. A. Berg, B. A. Berg, B. A. Berg, B. A. Berg, B. Hesselbo, C. Tsallis, D. A. Stariolo, E. Marinari, H. Kawai, I. Andricioaei, M. J. Sippl, M.-H. Hao, R. H. Swendsen, U. H. E. Hansmann, U. H. E. Hansmann, U. H. E. Hansmann, Ulrich H. E. Hansmann, Y. Okamoto, Yuko Okamoto   +20 more
core   +1 more source

Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]

, 2006
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M., Gallagher, S. M., Unterwald, E. M., Van Bockstaele, E. J.   +3 more
core   +2 more sources

Neuropeptide System Regulation of Prefrontal Cortex Circuitry: Implications for Neuropsychiatric Disorders

Frontiers in Neural Circuits, 2022
Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate various biological effects including membrane excitability, synaptic transmission and synaptogenesis, gene expression, and glial cell architecture and function. To date,
Sanne M. Casello, Rodolfo J. Flores, Hector E. Yarur, Huikun Wang, Monique Awanyai, Miguel A. Arenivar, Rosario B. Jaime-Lara, Rosario B. Jaime-Lara, Hector Bravo-Rivera, Hugo A. Tejeda   +9 more
doaj   +1 more source

Torsional path integral Monte Carlo method for the quantum simulation of large molecules [PDF]

, 2002
A molecular application is introduced for calculating quantum statistical mechanical expectation values of large molecules at nonzero temperatures. The Torsional Path Integral Monte Carlo (TPIMC) technique applies an uncoupled winding number formalism to
Clary, David C., Miller, Thomas F., III
core  

Structure of the Energy Landscape of Short Peptides

, 2002
We have simulated, as a showcase, the pentapeptide Met-enkephalin (Tyr-Gly-Gly-Phe-Met) to visualize the energy landscape and investigate the conformational coverage by the multicanonical method.
Berg B. A., Berg B. A., Eisenmenger F., HANDAN ARKIN, Hansmann U. H. E., TARIK ÇELİK   +5 more
core   +1 more source

Striatal Neuropeptides Enhance Selection and Rejection of Sequential Actions

Frontiers in Computational Neuroscience, 2017
The striatum is the primary input nucleus for the basal ganglia, and receives glutamatergic afferents from the cortex. Under the hypothesis that basal ganglia perform action selection, these cortical afferents encode potential “action requests.” Previous
David Buxton, Enrico Bracci, Paul G. Overton, Kevin Gurney   +3 more
doaj   +1 more source