Results 71 to 80 of about 42,525 (258)

The dopamine D1-D2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in basal ganglia

Frontiers in Neuroanatomy, 2011
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault, Melissa L. Perreault, Ahmed eHasbi, Ahmed eHasbi, Brian F. O'Dowd, Brian F. O'Dowd, Susan R. George, Susan R. George   +7 more
doaj   +1 more source

Generalized-ensemble Monte carlo method for systems with rough energy landscape

, 1997
We present a novel Monte Carlo algorithm which enhances equilibrization of low-temperature simulations and allows sampling of configurations over a large range of energies.
A. M. Ferrenberg, A. P. Lyubartsev, B. A. Berg, B. A. Berg, B. A. Berg, B. A. Berg, B. Hesselbo, C. Tsallis, D. A. Stariolo, E. Marinari, H. Kawai, I. Andricioaei, M. J. Sippl, M.-H. Hao, R. H. Swendsen, U. H. E. Hansmann, U. H. E. Hansmann, U. H. E. Hansmann, Ulrich H. E. Hansmann, Y. Okamoto, Yuko Okamoto   +20 more
core   +1 more source

Changes in Liver Metabolome Induced by Pterostilbene and Resveratrol in a Rat Model of Liver Steatosis

Molecular Nutrition &Food Research, EarlyView.
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela, Emily P. Laveriano‐Santos, Tania Portolés, Andreu Gual‐Grau, Juan Vicente Sancho, Maria P. Portillo   +5 more
wiley   +1 more source

Torsional path integral Monte Carlo method for calculating the absolute quantum free energy of large molecules [PDF]

, 2003
A new technique for evaluating the absolute free energy of large molecules is presented. Quantum-mechanical contributions to the intramolecular torsions are included via the torsional path integral Monte Carlo (TPIMC) technique.
Clary, David C., Miller, Thomas F., III
core  

Structure of the Energy Landscape of Short Peptides

, 2002
We have simulated, as a showcase, the pentapeptide Met-enkephalin (Tyr-Gly-Gly-Phe-Met) to visualize the energy landscape and investigate the conformational coverage by the multicanonical method.
Berg B. A., Berg B. A., Eisenmenger F., HANDAN ARKIN, Hansmann U. H. E., TARIK ÇELİK   +5 more
core   +1 more source

The distribution and functions of the enkephalins. [PDF]

Journal of Histochemistry & Cytochemistry, 1980
The enkephalins are two pentapeptides with pharmacological properties similar to narcotic drugs. These peptides are widely distributed in the central nervous system. The basal ganglia contain particularly high concentrations of enkaphalins. In the caudate nucleus ultrastructural studies show that enkephalin is contained within synaptic vesicles ...
Richard J. Miller, Virginia M. Pickel
openaire   +2 more sources

Anti‐Inflammatory and Antibacterial Properties of Curcuma longa Extract Against Helicobacter pylori

Molecular Nutrition &Food Research, EarlyView.
This study explored the effects of Curcuma longa extract (CLE) against H. pylori infection. CLE contained 18 chemical compounds and completely inhibited growth of H. pylori Sydney strain 1 (SS1) in vitro. In infected mice with H. pylori SS1, oral administration of CLE successfully eradicated H.
Jeongsook Kim, Kwan‐Woo Kim, Jin‐Kyu Jang, Myoung Jin Kim, Akila Cooray, Young‐Seob Lee, Kyu Pil Lee, Dae Young Lee   +7 more
wiley   +1 more source

Global Optimization by Energy Landscape Paving [PDF]

, 2002
We introduce a novel heuristic global optimization method, energy landscape paving (ELP), which combines core ideas from energy surface deformation and tabu search. In appropriate limits, ELP reduces to existing techniques.
C. J. McKnight, D. Cvijovic, D. J. Wales, F. Eisenmenger, F. Eisenmenger, F. Glover, F. Glover, G. Besold, J. Karle, L. T. Wille, L. Wesson, Luc T. Wille, M. J. Sippl, S. Kirkpatrick, T. Ooi, T. Schaumann, U. H. E. Hansmann, U. H. E. Hansmann, Ulrich H. E. Hansmann, W. Wenzel, Y. Duan, Y. Okamoto   +21 more
core   +3 more sources

Quality Control Strategies for Differentiation of Kalanchoe Species

Phytochemical Analysis, EarlyView.
ABSTRACT Kalanchoe species products are commercially available in local markets and by internationally accessible online retailers and may exhibit quality issues because of misidentification from similar common names and anatomical similarities among related species used as feedstock. This study proposes an approach using UPLC‐MS/MSE and HPTLC, coupled
Evelyn A. de Andrade, Isadora Machinski, Valter P. de Almeida, Sarah A. Barr, Wilmer H. Perera, Jane Manfron, Flávio L. Beltrame, R. Thomas Williamson, Wendy K. Strangman   +8 more
wiley   +1 more source

Methionine-enkephalin and leucine-enkephalin in human sympathoadrenal system and pheochromocytoma. [PDF]

Journal of Clinical Investigation, 1982
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with ...
Hiroo Imura, Shozo Li, Kazuwa Nakao, Hitoshi Ohtsuki, Takaaki Yoshimasa   +4 more
openaire   +2 more sources