Results 81 to 90 of about 46,429 (222)

Asthma induced by enkephalin. [PDF]

BMJ, 1980
A total of 291 diabetics were studied to see whether an asthmatic reaction was associated with facial flushing induced by chlorpropamide and alcohol. Of these patients, 191 reported facial flushing, of whom 12 reported breathlessness as well. Of these 12, five also described wheezing, and respiratory function tests showed them to have asthma.
David Pyke, Richard David Leslie, D Bellamy   +2 more
openaire   +3 more sources

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza, Marie Kempe, Sofia Grimmelsmann, Luiz Felipe Tavares, Ester Moreira De Castro‐Carletti, Angela Viegas Andrade, Liz Dennett, Harry Von Piekartz, Jorge Fuentes Contreras, Susan Armijo‐Olivo   +9 more
wiley   +1 more source

Stable Nitrogen Isotope Analysis of Amino Acids by Orbitrap Mass Spectrometry: Application for Extraterrestrial Samples

Rapid Communications in Mass Spectrometry, Volume 39, Issue 23, 15 December 2025.
ABSTRACT Background Obtaining isotopic data on soluble organic compounds, such as amino acids, in extraterrestrial samples is crucial for understanding their origins, prebiotic chemistry, and potential contamination. Conventional GC‐IRMS requires grams of material to measure isotopic compositions, limiting the analysis of low‐concentration organics in ...
O. M. McIntosh, A. A. Baczynski, M. Matney, H. L. McLain, K. K. Farnsworth, J. P. Dworkin, D. P. Glavin, J. E. Elsila, H. Xie, K. H. Freeman   +9 more
wiley   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

Wang-Landau molecular dynamics technique to search for low-energy conformational space of proteins

, 2007
Multicanonical molecular dynamics (MD) is a powerful technique for sampling conformations on rugged potential surfaces such as protein. However, it is notoriously difficult to estimate the multicanonical temperature effectively. Wang and Landau developed
Akira R. Kinjo, B. A. Berg, J. W. Neidigh, K. Morikami, Ken Nishikawa, P. Kollman, Takashi Mitsui, Takehiro Nagasima   +7 more
core   +1 more source

The use of genes for performance enhancement: doping or therapy? [PDF]

, 2011
Recent biotechnological advances have permitted the manipulation of genetic sequences to treat several diseases in a process called gene therapy. However, the advance of gene therapy has opened the door to the possibility of using genetic manipulation ...
Collares, T. F., Collares, T. V., Oliveira, R. S., Seixas, F. K., Smith, Kevin R.   +4 more
core   +5 more sources

Methionine-enkephalin and leucine-enkephalin in human sympathoadrenal system and pheochromocytoma. [PDF]

Journal of Clinical Investigation, 1982
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with ...
Hiroo Imura, Shozo Li, Kazuwa Nakao, Hitoshi Ohtsuki, Takaaki Yoshimasa   +4 more
openaire   +2 more sources

Rapid‐Onset Therapeutic Effects of Delta Opioid Receptor Agonists on Depression‐Like Behaviors Induced by Chronic Social Defeat Stress

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
Delta opioid receptor agonists improved social avoidance, depression, and anxiety‐like symptoms induced by chronic social defeat stress within 14 days of chronic administration. Furthermore, the therapeutic effects were observed earlier than with the existing antidepressant paroxetine (28 days).
Akihisa Tokuda, Yasuyuki Nagumo, Keita Kajino, Keita Iio, Katsuyasu Sakurai, Seiya Mizuno, Akiyoshi Saitoh, Tsuyoshi Saitoh, Hiroshi Nagase   +8 more
wiley   +1 more source

The dopamine D1-D2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in basal ganglia

Frontiers in Neuroanatomy, 2011
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault, Melissa L. Perreault, Ahmed eHasbi, Ahmed eHasbi, Brian F. O'Dowd, Brian F. O'Dowd, Susan R. George, Susan R. George   +7 more
doaj   +1 more source

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

Annals of Neurology, Volume 98, Issue 4, Page 777-787, October 2025.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim, Manyoel Lim, Thiago D. Nascimento, Frank Porreca, Robert A. Koeppe, Nouchine Hadjikhani, Alexandre F. DaSilva   +6 more
wiley   +1 more source