Results 11 to 20 of about 1,614 (199)

Sequence Divergence of the Enniatin Synthase Gene in Relation to Production of Beauvericin and Enniatins in Fusarium Species [PDF]

Toxins, 2013
Beauvericin (BEA) and enniatins (ENNs) are cyclic peptide mycotoxins produced by a wide range of fungal species, including pathogenic Fusaria. Amounts of BEA and ENNs were quantified in individual rice cultures of 58 Fusarium strains belonging to 20 ...
Agnieszka Waśkiewicz, Łukasz Stępień
doaj   +4 more sources

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages. [PDF]

J Appl Toxicol
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Frazzini S, Caloni F, Fossati P, Ruffo G, Rossi L.   +4 more
europepmc   +3 more sources

Enniatin Production Influences Fusarium avenaceum Virulence on Potato Tubers, but not on Durum Wheat or Peas

Pathogens, 2020
Fusarium avenaceum is a generalist pathogen responsible for diseases in numerous crop species. The fungus produces a series of mycotoxins including the cyclohexadepsipeptide enniatins.
Anas Eranthodi, Danielle Schneiderman, Linda J. Harris, Thomas E. Witte, Amanda Sproule, Anne Hermans, David P. Overy, Syama Chatterton, Jiajun Liu, Tao Li, Dianevys González-Peña Fundora, Weiquan Zhao, Nora A. Foroud   +12 more
doaj   +2 more sources

On the Potential Role of the (Pseudo-) Jahn–Teller Effect in the Membrane Transport Processes: Enniatin B and Beauvericin

Molecules, 2023
The molecular structure of mycotoxins enniatin B and beauvericin, which are used as ionophores, was studied using density functional theory in various symmetry groups and singly charged states.
Dagmar Štellerová, Vladimír Lukeš, Martin Breza   +2 more
doaj   +2 more sources

Untargeted Metabolomics Approach Correlated Enniatin B Mycotoxin Presence in Cereals with Kashin–Beck Disease Endemic Regions of China

Toxins, 2023
Kashin–Beck disease (KBD) is a multifactorial endemic disease that only occurs in specific Asian areas. Mycotoxin contamination, especially from the Fusarium spp., has been considered as one of the environmental risk factors that could provoke ...
Danlei Sun, Camille Chasseur, Françoise Mathieu, Jessica Lechanteur, Pierre Van Antwerpen, Joanne Rasschaert, Véronique Fontaine, Cédric Delporte   +7 more
doaj   +2 more sources

Biosynthesis of enniatin B [PDF]

FEBS Letters, 1976
The enniatins are cyclic depsihexapeptides with antibiotic properties and are produced by various strains of Fusarium [ 1,2] . Enniatin B, a lower analogue of valinomycin with a similar ionophoretic specificity for potassium ions [3], consists of three residues each of N-methyl-L-valine and 2-D-hydroxyisovaleric acid joined in an alternating fashion ...
Zocher, Rainer, Salnikow, Johann, Kleinkauf, Horst   +2 more
openaire   +2 more sources

Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer. [PDF]

, 2023
Low response rates and immune-related adverse events limit the remarkable impact of cancer immunotherapy. To improve clinical outcomes, preclinical studies have shown that combining immunotherapies with N-terminal Hsp90 inhibitors resulted in improved ...
Lu, Sumin, Munn, David, Rodriguez, Paulo C, Celis, Esteban, Jilani, Yasmeen, Marasco, Daniela, Debbab, Abdessamad, Eisa, Nada H, Korkaya, Hasan, Kommalapati, Vamsi Krishna, Tsai, Francis T F, Kainth, Kashish, El Andaloussi, Abdeljabar, Crowley, Vincent M, Elahi, Asif, Llbiyi, Taoufik, Chadli, Ahmed, Blagg, Brian, Serwetnyk, Michael A, Lee, Sukyeong   +19 more
core   +3 more sources

Beauvericin and Enniatins: In Vitro Intestinal Effects [PDF]

Toxins, 2020
Food and feed contamination by emerging mycotoxins beauvericin and enniatins is a worldwide health problem and a matter of great concern nowadays, and data on their toxicological behavior are still scarce. As ingestion is the major route of exposure to mycotoxins in food and feed, the gastrointestinal tract represents the first barrier encountered by ...
Bertero A., Fossati P., Tedesco D. E. A., Caloni F.   +3 more
openaire   +4 more sources

Cyclodepsipeptide Biosynthesis in Hypocreales Fungi and Sequence Divergence of The Non-Ribosomal Peptide Synthase Genes

Pathogens, 2020
Fungi from the Hypocreales order synthesize a range of toxic non-ribosomal cyclic peptides with antimicrobial, insecticidal and cytotoxic activities. Entomopathogenic Beauveria, Isaria and Cordyceps as well as phytopathogenic Fusarium spp.
Monika Urbaniak, Agnieszka Waśkiewicz, Artur Trzebny, Grzegorz Koczyk, Łukasz Stępień   +4 more
doaj   +1 more source

Biological Detoxification of Enniatins [PDF]

, 2022
Summary: Mycotoxins are secondary metabolites produced by fungi. Enniatins are a group of cyclohexadepsipeptides made of three hydroxyisovaleric acid molecules and alternating amino acids mostly valine, leucine and isoleucine. Enniatins have been associated with mainly cereal and cereal-based products, but also with nuts and some dried fruits. There is
Suchfort, Rosine Ghislaine, Karlovsky, Petr, Georg-August-Universität Göttingen, Karlovsky, Petr, Yli-Mattila, Tapani   +4 more
openaire   +2 more sources