Results 11 to 20 of about 11,957 (196)

Nuclear receptor control of enterohepatic circulation. [PDF]

open access: yesCompr Physiol, 2012
AbstractEnterohepatic circulation is responsible for the capture of bile acids and other steroids produced or metabolized in the liver and secreted to the intestine, for reabsorption back into the circulation and transport back to the liver. Bile acids are secreted from the liver in the form of mixed micelles that also contain phosphatidylcholines and ...
Gonzalez FJ.
europepmc   +3 more sources

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive InhibitionSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a membrane-bound transcription factor involved in the maintenance of lipid metabolism in the liver and small intestine. CREB3L3 controls hepatic triglyceride and glucose
Yoshimi Nakagawa   +18 more
doaj   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Enterohepatic Circulation of Bilirubin [PDF]

open access: yesNature, 1961
THE enterohepatic circulation of bile pigment has been the subject of protracted debate. Recirculation of bilirubin, and its bacterial reduction products, the urobilinoids, has been postulated and denied1. The availability of bilirubin labelled with carbon-14 in this Laboratory2 has obviated many of the problems previously inherent in the study of ...
R, LESTER, J D, OSTROW, R, SCHMID
openaire   +2 more sources

Oleandrin: A Systematic Review of its Natural Sources, Structural Properties, Detection Methods, Pharmacokinetics and Toxicology

open access: yesFrontiers in Pharmacology, 2022
Oleandrin is a highly lipid-soluble cardiac glycoside isolated from the plant Nerium oleander (Apocynaceae) and is used as a traditional herbal medicine due to its excellent pharmacological properties. It is widely applied for various disease treatments,
Jinxiao Zhai   +4 more
doaj   +1 more source

Exploitation of Bile Acid Transport Systems in Prodrug Design

open access: yesMolecules, 2007
The enterohepatic circulation of bile acids is one of the most efficient recycling routes in the human body. It is a complex process involving numerous transport proteins, which serve to transport bile acids from the small intestine into portal ...
Elina Sievänen
doaj   +1 more source

Recent advances in understanding and managing cholestasis [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Cholestatic liver diseases are hereditary or acquired disorders with impaired hepatic excretion and enterohepatic circulation of bile acids and other cholephiles.
Martin Wagner, Michael Trauner
doaj   +1 more source

Role of Saccharomyces boulardii in Reduction of Neonatal Hyperbilirubinemia [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Probiotics are known to reduce the severity of hyperbilirubinemia. Aim: This study was done to evaluate the effect of probiotic on neonatal hyperbilirubinemia in term neonates. Materials and Methods: A total of 181 healthy term neonates
V. Suganthi, A. Gokul Das
doaj   +1 more source

Bile Acids: Major Regulator of the Gut Microbiome

open access: yesMicroorganisms, 2022
Bile acids are synthesized from cholesterol and play an important role in regulating intestinal microflora. The different degrees of hydrophobicity and acidity of individual bile acids may affect their antimicrobial properties.
Chihyeok An   +14 more
doaj   +1 more source

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