Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization [PDF]
, 2019 Author summary The intestinal epithelium is a crucial biological interface, interacting with both commensal and pathogenic microorganisms. It’s lined with heavily glycosylated proteins and glycolipids which can act as both attachment sites and energy ...
Baines, J. +12 more
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Potential of human norovirus surrogates and Salmonella enterica contamination of pre-harvest basil (Ocimum basilicum) via leaf surface and plant substrate [PDF]
, 2018 Fresh produce has been identified as an important vehicle for foodborne pathogen transmission and fresh culinary herbs have occasionally been associated with human pathogens and illness. In this study, the fate of human NoV surrogates [murine norovirus 1
Li, Dan, Uyttendaele, Mieke
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Human Intestinal Enteroids Model MHC-II in the Gut Epithelium
Frontiers in Immunology, 2019 The role of intestinal epithelial cells (IECs) in mucosal tolerance and immunity remains poorly understood. We present a method for inducing MHC class II (MHC-II) in human enteroids, “mini-guts” derived from small intestinal crypt stem cells, and show ...
Jonathan E. Wosen +9 more
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Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection [PDF]
, 2018 Several viruses induce intestinal epithelial cell death during enteric infection. However, it is unclear whether proapoptotic capacity promotes or inhibits replication in this tissue.
Aravamudhan, Pavithra +12 more
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Frontiers in Cellular and Infection MicrobiologyInfection of ruminants such as cattle with Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease, a disease characterized by chronic inflammation of the small intestine and diarrhoea.
Omar A. Alfituri +5 more
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Congenital diarrhoeal disorders: advances in this evolving web of inherited enteropathies. [PDF]
, 2015 Congenital diarrhoeal disorders (CDDs) represent an evolving web of rare chronic enteropathies, with a typical onset early in life. In many of these conditions, severe chronic diarrhoea represents the primary clinical manifestation, whereas in others ...
BERNI CANANI, ROBERTO +4 more
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Establishment and long-term maintenance of primary intestinal epithelial cells cultured from the rainbow trout,Oncorhynchus mykiss. [PDF]
, 2018 A novel method for the establishment and long-term maintenance ofex vivocultures from intestinal regions of the rainbow trout,Oncorhynchus mykiss(Walbaum), is reported. Adherence of cells was observed within hours, epithelial island formation recorded at
Beaulieu +5 more
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Development of in vitro enteroids derived from bovine small intestinal crypts
Veterinary Research, 2018 Cattle are an economically important domestic animal species. In vitro 2D cultures of intestinal epithelial cells or epithelial cell lines have been widely used to study cell function and host–pathogen interactions in the bovine intestine. However, these
Carly A. Hamilton +10 more
doaj +1 more source
Working with patient-derived enteroids and colonoids v1
, 2023 This is a compilations of working with patient-derived enteroids or colonoids, from recovery to cryopreservation, in expansion culture (minimal differentiation)
openaire +1 more source
DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging. [PDF]
, 2020 Background & aimsThe epithelia of the intestine and colon turn over rapidly and are maintained by adult stem cells at the base of crypts. Although the small intestine and colon have distinct, well-characterized physiological functions, it remains ...
Coppola, Giovanni +5 more
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