Results 41 to 50 of about 24,141 (234)
Frontiers in Cell and Developmental Biology, 2020 Murine development demands that pluripotent epiblast stem cells in the peri-implantation embryo increase from approximately 120 to 14,000 cells between embryonic days (E) 4.5 and E7.5. This is possible because epiblast stem cells can complete cell cycles
Georgia R. Kafer, Anthony J. Cesare
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YAP establishes epiblast responsiveness to inductive signals for germ cell fate
Development, 2021 The germ cell lineage in mammals is induced by the stimulation of pluripotent epiblast cells by signaling molecules. Previous studies have suggested that the germ cell differentiation competence or responsiveness of epiblast cells to signaling molecules ...
Saya Kagiwada +9 more
semanticscholar +1 more source
Distinct modes of floor plate induction in the chick embryo [PDF]
, 2003 To begin to reconcile models of floor plate formation in the vertebrate neural tube, we have performed experiments aimed at understanding the development of the early floor plate in the chick embryo. Using real-time analyses of cell behaviour, we provide
Fraser, Scott +4 more
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eLife, 2015 Early mouse development is accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2), which is essential for embryonic development.
Jan J Zylicz +6 more
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Sox2 Level Is a Determinant of Cellular Reprogramming Potential. [PDF]
PLoS ONE, 2013 Epiblast stem cells (EpiSCs) and embryonic stem cells (ESCs) differ in their in vivo differentiation potential. While ESCs form teratomas and efficiently contribute to the development of chimeras, EpiSCs form teratomas but very rarely chimeras.
Dong Wook Han +7 more
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Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
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Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State
Stem Cells International, 2021 Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5 ...
A. S. Devika +5 more
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Specific epiblast loss and hypoblast impairment in cattle embryos sensitized to survival signalling by ubiquitous overexpression of the proapoptotic gene BAD. [PDF]
PLoS ONE, 2014 Early embryonic lethality is common, particularly in dairy cattle. We made cattle embryos more sensitive to environmental stressors by raising the threshold of embryo survival signaling required to overcome the deleterious effects of overexpressing the ...
Jessica van Leeuwen +4 more
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eLife, 2022 The epiblast of vertebrate embryos is comprised of neural and non-neural ectoderm, with the border territory at their intersection harboring neural crest and cranial placode progenitors.
Ruth M Williams +3 more
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Measurement of junctional tension in epithelial cells at the onset of primitive streak formation in the chick embryo via non-destructive optical manipulation [PDF]
, 2020 Directional cell intercalations of epithelial cells during gastrulation has in several organisms been shown to be associated with a planar cell polarity in the organisation of the actin-myosin cytoskeleton and is postulated to reflect directional tension
Antin +39 more
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