Results 61 to 70 of about 24,553 (253)
Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. [PDF]
, 2018 Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches.
Castillo-Azofeifa, David +7 more
core +1 more source
Nature of the hypoblastic influence on the chick embryo epiblast [PDF]
Development, 1983 ABSTRACT Stage XIII chick blastoderms deprived of the marginal zone, the area opaca and the posterior half of the hypoblast, when incubated further developed axes whose orientation in 50 % of the cases was according to the original blastoderm’s orientation, whilst in 50 % of the cases they developed at 90° from the posterior side.
E, Mitrani, Y, Shimoni, H, Eyal-Giladi
openaire +2 more sources
Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
Stem Cell Research, 2018 We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Cherry dual reporter system.
Ryan P. Russell +3 more
doaj +1 more source
Nuclear re-organisation of the Hoxb complex during mouse embryonic development [PDF]
, 2005 The spatial and temporal co-linear expression of Hox genes during development is an exquisite example of programmed gene expression. The precise mechanisms underpinning this are not known.
Bickmore, Wendy A +3 more
core +2 more sources
Asymmetry in the frequency and position of mitosis in the mouse embryo epiblast at gastrulation
EMBO Reports, 2020 At gastrulation, a subpopulation of epiblast cells constitutes a transient posteriorly located structure called the primitive streak, where cells that undergo epithelial–mesenchymal transition make up the mesoderm and endoderm lineages.
Navrita Mathiah +7 more
semanticscholar +1 more source
Cell Reports, 2017 Summary: The mouse inner cell mass (ICM) segregates into the epiblast and primitive endoderm (PrE) lineages coincident with implantation of the embryo. The epiblast subsequently undergoes considerable expansion of cell numbers prior to gastrulation.
Hisham Mohammed +11 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Stem Cell Reports, 2023 Summary: Naive human pluripotent stem cells (hPSCs) are defined as the in vitro counterpart of the human preimplantation embryo’s epiblast and are used as a model system to study developmental processes.
Marta Moya-Jódar +13 more
doaj +1 more source
Competence, specification and commitment in otic placode induction [PDF]
, 2000 The inner ear is induced from cranial ectoderm adjacent to the hindbrain. Despite almost a century of study, the molecular mechanisms of inner ear induction remain obscure. We have identified four genes expressed very early in the anlage of the inner ear,
Bronner-Fraser, Marianne +1 more
core
Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo [PDF]
, 2014 Here, we exploit the spatial separation of temporal events of neural differentiation in the elongating chick body axis to provide the first analysis of transcriptome change in progressively more differentiated neural cell populations in vivo.
Abranches +57 more
core +5 more sources