Results 51 to 60 of about 24,553 (253)

Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State

Stem Cells International, 2021
Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5 ...
A. S. Devika, Anna Montebaur, S. Saravanan, Raghu Bhushan, Frederic Koch, Smita Sudheer   +5 more
doaj   +1 more source

Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm [PDF]

, 2018
Networks of interacting co-regulated genes distinguish the inner cell mass (ICM) from the differentiated trophectoderm (TE) in the preimplantation blastocyst, in a species specific manner.
Bates, Nicola, Brison, Daniel R., Garner, Terence, Kimber, Susan J., Minogue, Ben, Oldershaw, Rachel, Shaw, Lisa, Smith, Helen, Sneddon, Sharon, Stevens, Adam   +9 more
core   +1 more source

Epiblast and trophoblast morphogenesis in the pre‐gastrulation blastocyst of the pig. A light‐ and electron‐microscopical study

Journal of morphology, 2021
The epiblast of the amniote embryo is of paramount importance during early development as it gives rise to all tissues of the embryo proper. In mammals, it emerges through segregation of the hypoblast from the inner cell mass and subsequently undergoes ...
Braah Harmoush, N. Tsikolia, C. Viebahn
semanticscholar   +1 more source

Successful reprogramming of epiblast stem cells by blocking nuclear localization of β-catenin. [PDF]

, 2014
Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts.
Hayama, Tomonari, Masaki, Hideki, Murayama, Hideyuki, Nakauchi, Hiromitsu, Sato, Hideyuki, Yamaguchi, Tomoyuki   +5 more
core   +5 more sources

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells. [PDF]

PLoS ONE, 2016
Fibroblast growth factor 5 (Fgf5) has been widely used as a marker for the epiblast in the postimplantation embryo and epiblast stem cells (mEpiSCs) in the mouse, making it valuable for study of differentiation of various tissues and epiblast cells in ...
Le Tran Phuc Khoa, Takuya Azami, Tomoyuki Tsukiyama, Jun Matsushita, Setsuko Tsukiyama-Fujii, Satoru Takahashi, Masatsugu Ema   +6 more
doaj   +1 more source

Short-Circuiting Epiblast Development [PDF]

Cell Stem Cell, 2007
Although human and mouse embryonic stem cells share many characteristics, their behaviors are not identical. Two recent papers describe the derivation of stem cell lines from mouse epiblast that may provide an explanation for the unique character of human embryonic stem cells.
openaire   +2 more sources

Single-cell atlas of early chick development reveals gradual segregation of neural crest lineage from the neural plate border during neurulation

eLife, 2022
The epiblast of vertebrate embryos is comprised of neural and non-neural ectoderm, with the border territory at their intersection harboring neural crest and cranial placode progenitors.
Ruth M Williams, Martyna Lukoseviciute, Tatjana Sauka-Spengler, Marianne E Bronner   +3 more
doaj   +1 more source

Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation [PDF]

, 2017
In cattle early gastrulation-stage embryos (Stage 5), four tissues can be discerned: (i) the top layer of the embryonic disc consisting of embryonic ectoderm (EmE); (ii) the bottom layer of the disc consisting of mesoderm, endoderm and visceral hypoblast
Berg, D, Maclean, P, Pfeffer, P, Smith, C   +3 more
core   +2 more sources

Temporally resolved early bone morphogenetic protein-driven transcriptional cascade during human amnion specification

eLife
Amniogenesis, a process critical for continuation of healthy pregnancy, is triggered in a collection of pluripotent epiblast cells as the human embryo implants.
Nikola Sekulovski, Jenna C Wettstein, Amber E Carleton, Lauren N Juga, Linnea E Taniguchi, Xiaolong Ma, Sridhar Rao, Jenna K Schmidt, Thaddeus G Golos, Chien-Wei Lin, Kenichiro Taniguchi   +10 more
doaj   +1 more source

MCRS1 is essential for epiblast development during early mouse embryogenesis

Reproduction, 2020
Microspherule protein 1 (MCRS1, also known as MSP58) is an evolutionarily conserved protein that has been implicated in various biological processes. Although a variety of functions have been attributed to MCRS1 in vitro, mammalian MCRS1 has not been ...
Wei Cui, Agnes Cheong, Yongsheng Wang, Yuran Tsuchida, Yong Liu, K. Tremblay, J. Mager   +6 more
semanticscholar   +1 more source