Results 61 to 70 of about 10,666 (158)
In Vivo Differentiation Potential of Epiblast Stem Cells Revealed by Chimeric Embryo Formation
Cell Reports, 2012 Chimera formation after blastocyst injection or morula aggregation is the principal functional assay of the developmental potential of mouse embryonic stem cells (ESCs).
Yali Huang +3 more
doaj +1 more source
The epigenetic modifier Fam208a is required to maintain epiblast cell fitness
Scientific Reports, 2017 Gastrulation initiates with the formation of the primitive streak, during which, cells of the epiblast delaminate to form the mesoderm and definitive endoderm.
Shohag Bhargava +8 more
doaj +1 more source
Stem Cell Reports, 2017 In early mouse pre-implantation development, primitive endoderm (PrE) precursors are platelet-derived growth factor receptor alpha (PDGFRα) positive. Here, we demonstrated that cultured mouse embryonic stem cells (mESCs) express PDGFRα heterogeneously ...
Antonio Lo Nigro +14 more
doaj +1 more source
Cell Reports, 2019 Summary: Following implantation, the epiblast (EPI) cells transit from the naive to primed pluripotency, accompanied by dynamic changes in X chromosome activity in females. To investigate the molecular attributes of this process, we performed single-cell
Shangli Cheng +7 more
doaj +1 more source
ZMYM2 inhibits NANOG-mediated reprogramming [version 1; peer review: 2 approved]
Wellcome Open Research, 2019 Background: NANOG is a homeodomain-containing transcription factor which forms one of the hubs in the pluripotency network and plays a key role in the reprogramming of somatic cells and epiblast stem cells to naïve pluripotency.
Moyra Lawrence +4 more
doaj +1 more source
Pluripotency Potential of Embryonic Stem Cell-Like Cells Derived from Mouse Testis
Cell Journal, 2019 Objective: During the cultivation of spermatogonial stem cells (SSCs) and their conversion into embryonic stem-like (ES-like) cells, transitional ES-like colonies and epiblast-like cells were observable.
Hossein Azizi +2 more
doaj +1 more source
A Method to Identify and Isolate Pluripotent Human Stem Cells and Mouse Epiblast Stem Cells Using Lipid Body-Associated Retinyl Ester Fluorescence [PDF]
, 2014 Thangaselvam Muthusamy +4 more
openalex +1 more source
Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation [PDF]
, 2016 M. Felicia Basilicata +4 more
openalex +1 more source
Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions
Cell Reports, 2013 Embryonic stem cells (ESCs) are derived from mammalian embryos during the transition from totipotency, when individual blastomeres can make all lineages, to pluripotency, when they are competent to make only embryonic lineages.
Sophie M. Morgani +6 more
doaj +1 more source