Results 111 to 120 of about 34,062 (265)

Some phenolic compounds as inhibitors of glutathione s-transferase and glutathione reductase: an in vitro and in silico analysis

Journal of Ata-Chem, 2023
It has been determined that Glutathione S-transferases (GSTs) and Glutathione reductase (GR) activities increase in cancer cells and contribute to the progression of cancer by causing multidrug resistance (MDR).
Pınar Güller
doaj  

In vitro bioactivity of various pure flavonoids in ruminal fermentation, with special reference to methane formation

Czech Journal of Animal Science, 2018
Polyphenols, like flavonoids, have been investigated when present in intact plants or in extracts as methane mitigating dietary supplements in ruminants. The aim of the present study was to examine pure compounds in a short-term in vitro experiment using
Susanne Sinz, Carmen Kunz, Annette Liesegang, Ueli Braun, Svenja Marquardt, Carla R. Soliva, Michael Kreuzer   +6 more
doaj   +1 more source

Unveiling contrasting iron efficiency strategies in common bean (Phaseolus vulgaris L.) genotypes under iron deficiency

Plant Biology, EarlyView.
Common bean genotypes differ in their iron acquisition through distinct Strategy I responses and root exudation patterns. Abstract Iron (Fe) deficiency in food crops, particularly on calcareous soils, limits productivity and human nutrition. This study investigated two common bean (Phaseolus vulgaris) genotypes, Guaymí (high Fe‐accumulating, HI) and ...
F. X. Rucamumihigo, U. Ludewig, A. Hernández‐Pridybailo, I. Cakmak, N. J. Maywald   +4 more
wiley   +1 more source

Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on δ-opioid receptor stimulation

, 2010
Epicatechin, a flavonoid, is a well-known antioxidant linked to a variety of protective effects in both humans and animals. In particular, its role in protection against cardiovascular disease has been demonstrated by epidemiologic studies.
Brian P. Head, Piyush M. Patel, Yousuke T. Horikawa, Michelle Saldana, Nancy D. Dalton, David M. Roth, Jacqueline A. Bonds, Mathivadhani Panneerselvam, Yasuo M. Tsutsumi, Hemal H. Patel   +9 more
core   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

(Poly)phenols: Mechanisms of action and efficacy of contemporary supplements for exercise recovery and performance

Experimental Physiology, EarlyView.
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley   +1 more source

(-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons

, 2007
Emerging evidence suggests that the cellular actions of flavonoids relate not simply to their antioxidant potential but also to the modulation of protein kinase signalling pathways. We investigated in primary cortical neurons, the ability of the flavan-3-
Parmvir Bahia, Cadenas, E, Cadenas, E., Marcus Rattray, Bahia, P., Enrique Cadenas, Schroeter, H, Williams, R.J., Hagen Schroeter, Sheppard, O, Spencer, J.P.E., Bahia, P, Rice-Evans, C, Robert J. Williams, Jeremy P. E. Spencer, Williams, RJ, Rice-Evans, C., Olivia Sheppard, Spencer, JPE, Rattray, M, Rattray, M., Catherine Rice‐Evans, Schroeter, H., Sheppard, O.   +23 more
core   +1 more source

Apoptosis Induced by (−)-Epicatechin in Human Breast Cancer Cells is Mediated by Reactive Oxygen Species

, 2020
(−)-Epicatechin is a phenolic compound with antioxidant activity that is present in natural food and drinks, such as cocoa and red wine. Evidence suggests that (−)-epicatechin exhibits anticancer activity; however, its mechanism of action is ...
José Rubén García-Sánchez, Fernando Pereyra-Vergara, Ivonne María Olivares-Corichi, Juan Pedro Luna-Arias, Adriana Guadalupe Perez-Ruiz   +4 more
core   +1 more source

Constituents of a fern, Davallia mariesii Moore. II. Identification and 1H- and 13C-nuclear magnetic resonance spectra of procyanidin B-5, epicatechin-(4 beta----8)-epicatechin-(4 beta----6)-epicatechin, and epicatechin-(4 beta----6)-epicatechin-(4 beta----8)-epicatechin-(4 beta----6)-epicatechin.

Chemical & pharmaceutical bulletin, 1992
Procyanidin B-5 (1), epicatechin-(4 beta----8)-epicatechin-(4 beta----6)-epicatechin (2), and epicatechin-(4 beta----6)-epicatechin-(4 beta----8)-epicatechin-(4 beta----6)-epicatechin (3), which showed an inhibitory effect toward protein kinase C, were isolated from the rhizomes of Davallia mariesii Moore. Detailed analyses of their 1H- and 13C-nuclear
C B, Cui, Y, Tezuka, T, Kikuchi, H, Nakano, T, Tamaoki, J H, Park   +5 more
openaire   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source