Results 221 to 230 of about 31,210 (261)

Pharmacokinetics of (−)-epicatechin in rabbits

Archives of Pharmacal Research, 2009
The aim of this study was to investigate the pharmacokinetics of (-)-epicatechin (EC) in rabbits after intravenous, intraperitoneal, and oral administration. A two-compartment model was used to describe the pharmacokinetics of EC after intravenous administration. EC showed dose-independent pharmacokinetics after intravenous administration. In addition,
Yen-An, Chen, Kuang-Yang, Hsu
openaire   +2 more sources

Influence of Gallate and Pyrogallol Moieties on the Intestinal Absorption of (−)‐Epicatechin and (−)‐Epicatechin Gallate

Journal of Food Science, 2012
Abstract:  The cellular accumulation of individual catechins was measured as an index of intestinal absorption to clarify the interactions among catechins. The cellular accumulation of (−)‐epicatechin (EC) increased in the presence of other catechins.
Tomohiko, Tagashira, Tominari, Choshi, Satoshi, Hibino, Jun, Kamishikiryou, Narumi, Sugihara   +4 more
openaire   +2 more sources

Insulin like activity in (−) epicatechin

Acta Diabetologica Latina, 1989
Water extract of the bark of plant of Pterocarpus marsupium Roxb is used as an antidiabetic drug in indigenous medicine in India. (-) Epicatechin, its active principle, has been found to be insulinogenic. The present in vitro study reports some insulin like activities of (-) epicatechin.
F, Ahmad, P, Khalid, M M, Khan, A K, Rastogi, J R, Kidwai   +4 more
openaire   +2 more sources

Does epicatechin contribute to the acute vascular function effects of dark chocolate? A randomized, crossover study

Molecular Nutrition and Food Research, 2016
Scope: Cocoa, rich in flavan-3-ols, improves vascular function, but the contribution of specific flavan-3-ols is unknown. We compared the effects of pure epicatechin, a major cocoa flavan-3-ol, and chocolate.
Johanna M Geleijnse, Paul A Kroon, Mark Philo   +2 more
exaly   +2 more sources

Protective Effect of Epicatechin, Epicatechin Gallate, and Quercetin on Lipid Peroxidation in Phospholipid Bilayers

Archives of Biochemistry and Biophysics, 1994
Antioxidative effect of (-)-epicatechin,(-)-epicatechin gallate, and quercetin was examined by measuring the inhibition of lipid peroxidation in large unilamellar liposomes composed of egg yolk phosphatidylcholine (PC). These catechol-type flavonoids were stable in the liposomal suspension.
J, Terao, M, Piskula, Q, Yao
openaire   +2 more sources

Advances in physiological functions and mechanisms of (−)-epicatechin

Critical Reviews in Food Science and Nutrition, 2020
(-)-Epicatechin (EC) is a flavanol easily obtained through the diet and is present in tea, cocoa, vegetables, fruits, and cereals. Recent studies have shown that EC protects human health and exhibits prominent anti-oxidant and anti-inflammatory activities, enhances muscle performance, improves symptoms of cardiovascular and cerebrovascular diseases ...
Zhihao Qu, Ailing Liu, Penghui Li, Changwei Liu, Wenjun Xiao, Jianan Huang, Zhonghua Liu, Sheng Zhang   +7 more
openaire   +2 more sources

Cardioprotective effect of (-) epicatechin

Atherosclerosis, 2014
Nutrition and ...
Novaković, Aleksandra, Vranić, Aleksandra, Janković, Goran, Stojanović, Ivan, Milojević, Predrag, Ugrešić, Nenad, Kanjuh, Vladimir, Yang, Qin, Guo-Wei, H.   +8 more
openaire   +2 more sources

Effects of epicatechin on rat islets of Langerhans

Diabetes, 1984
Plants containing epicatechin (a flavonoid) have been used to treat diabetes mellitus in Indian medicine. The present study reports effects of this compound on isolated islets of Langerhans. The flavonoid (1 mM) was found to increase insulin secretion from isolated rat islets of Langerhans in the presence of either 2 or 20 mM glucose, in static ...
C S, Hii, S L, Howell
openaire   +2 more sources

Trapping of Carbonyl Compounds by Epicatechin: Reaction Kinetics and Identification of Epicatechin Adducts in Stored UHT Milk

Journal of Agricultural and Food Chemistry, 2020
The kinetics of the reaction between epicatechin and various carbonyl compounds typically formed in cooked and stored foods were evaluated in model systems at pH 7.4 and 37 °C, and the corresponding reaction products in stored ultrahigh temperature (UHT) milk-added epicatechin were identified by high-performance liquid chromatography-tandem mass ...
Hongkai Zhu, Mahesha M Poojary, Mogens L Andersen   +2 more
exaly   +4 more sources

Epicatechin: Endothelial Function and Blood Pressure

Journal of Agricultural and Food Chemistry, 2012
Epidemiological studies indicate an inverse relationship between flavanol intake and the risk of cardiovascular disease. Potential mechanisms include their effects on endothelial function and hypertension. A number of studies have shown that flavanol-rich cocoa reduces blood pressure and endothelial dysfunction, whereas black tea may have opposite ...
Rosario, Jiménez, Juan, Duarte, Francisco, Perez-Vizcaino   +2 more
openaire   +2 more sources