Results 21 to 30 of about 92,135 (253)
Epidermal Barrier in Atopic Dermatitis [PDF]
Allergy, Asthma and Immunology Research, 2012 Atopic dermatitis (AD) is a complex disease that affects up to 20% of children and impacts the quality of patients and families in a significant manner. New insights into the pathophysiology of AD point to an important role of structural abnormalities in the epidermis combined with immune dysregulation.
Kim, Byung Eui, Leung, Donald YM
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Therapeutic benefits of enhancing permeability barrier for atopic eczema
Dermatologica Sinica, 2015 The regulatory role of epidermal permeability barrier function in cutaneous inflammation has been well appreciated. While barrier disruption induces cutaneous inflammation, improvement of permeability barrier function alleviates inflammation.
George Man +2 more
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Modern View on the Role of Epidermal Barrier in Atopic Phenotype Development in Children
Вопросы современной педиатрии, 2020 Epidermal barrier is one is one of the most important structures of the skin, it performs protective function, ensure internal environment constancy by selective ions and molecules transport and by transepidermal water loss regulation.
Nikolay N. Murashkin +5 more
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Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities
Вопросы современной педиатрии, 2021 Atopic dermatitis (AtD) is multifactorial inflammatory skin disease, one of the aspects of its pathogenesis is epidermal barrier dysfunction. Early development of AtD is associated with filaggrin dysfunction.
Nikolay N. Murashkin +6 more
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Transepidermal water loss: the signal for recovery of barrier structure and function.
Journal of Lipid Research, 1989 Previous studies have demonstrated that perturbations in barrier function stimulate epidermal lipid synthesis and that this increase can be prevented by occlusive membranes.
G Grubauer, P M Elias, K R Feingold
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Journal of Lipid Research, 1992 Disruption of the permeability barrier results in an increase in cholesterol synthesis in the epidermis. Inhibition of cholesterol synthesis impairs the repair and maintenance of barrier function.
S M Jackson +6 more
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Epidermal Barrier Dysfunction in Atopic Dermatitis
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2021 Impaired skin barrier is one of the hallmarks of atopic dermatitis (AD), with abnormalities in the cornified envelope, lipid lamellae, tight junctions and cutaneous microbiome.
Tiago Fernandes Gomes +2 more
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Journal of Investigative Dermatology, 1961 The barrier to epidermal absorption and to water loss has been given much attention in recent years (1, 3, 5, 7, 8, 10). The purpose of this paper is not to consider the location of the barrier or the mechanism of penetration but rather to report the differences between the functional barrier of scrotal skin and that of abdominal skin and mucous ...
Smith Jr., J. Graham +2 more
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Bricks and mortar of the epidermal barrier [PDF]
Experimental & Molecular Medicine, 1999 A specialized tissue type, the keratinizing epithelium, protects terrestrial mammals from water loss and noxious physical, chemical and mechanical insults. This barrier between the body and the environment is constantly maintained by reproduction of inner living epidermal keratinocytes which undergo a process of terminal differentiation and then ...
Z, Nemes, P M, Steinert
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Permeability barrier requirements regulate epidermal beta-glucocerebrosidase.
Journal of Lipid Research, 1994 The intercellular spaces of the outermost layers of the epidermis (stratum corneum, SC) of terrestrial mammals contain a mixture of lipids, enriched in ceramides that are critical for the epidermal permeability barrier. Whereas glucosylceramides (GlcCer)
W M Holleran +6 more
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