Results 31 to 40 of about 2,098,761 (326)
Cold Spring Harbor Perspectives in Medicine, 2014 The epidermis functions as a physical barrier to the external environment and works to prevent loss of water from the skin. Numerous factors have been implicated in the formation of epidermal barriers, such as cornified envelopes, corneocytes, lipids, junctional proteins, proteases, protease inhibitors, antimicrobial peptides, and transcription factors.
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Epidermal Barrier in Atopic Dermatitis [PDF]
Allergy, Asthma and Immunology Research, 2012 Atopic dermatitis (AD) is a complex disease that affects up to 20% of children and impacts the quality of patients and families in a significant manner. New insights into the pathophysiology of AD point to an important role of structural abnormalities in the epidermis combined with immune dysregulation.
Kim, Byung Eui, Leung, Donald YM
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Herbal medicines that benefit epidermal permeability barrier function
Dermatologica Sinica, 2015 Epidermal permeability barrier function plays a critical role in regulating cutaneous functions. Hence, researchers have been searching for effective and affordable regimens to enhance epidermal permeability barrier function.
Lizhi Hu +3 more
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Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation
Biology, 2022 The skin epidermis, with its capacity for lifelong self-renewal and rapid repairing response upon injury, must maintain an active status in metabolism.
Juan Wang, Sabine A. Eming, Xiaolei Ding
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Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]
, 2018 The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela +5 more
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Therapeutic benefits of enhancing permeability barrier for atopic eczema
Dermatologica Sinica, 2015 The regulatory role of epidermal permeability barrier function in cutaneous inflammation has been well appreciated. While barrier disruption induces cutaneous inflammation, improvement of permeability barrier function alleviates inflammation.
George Man +2 more
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Modern View on the Role of Epidermal Barrier in Atopic Phenotype Development in Children
Вопросы современной педиатрии, 2020 Epidermal barrier is one is one of the most important structures of the skin, it performs protective function, ensure internal environment constancy by selective ions and molecules transport and by transepidermal water loss regulation.
Nikolay N. Murashkin +5 more
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Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities
Вопросы современной педиатрии, 2021 Atopic dermatitis (AtD) is multifactorial inflammatory skin disease, one of the aspects of its pathogenesis is epidermal barrier dysfunction. Early development of AtD is associated with filaggrin dysfunction.
Nikolay N. Murashkin +6 more
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Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells [PDF]
, 2019 Claudins regulate paracellular permeability in different tissues. The claudin-binding domain of Clostridium perfringens enterotoxin (cCPE) is a known modulator of a claudin subset. However, it does not efficiently bind to claudin-1 (Cldn1).
Beier, Laura-Sophie +12 more
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Transepidermal water loss: the signal for recovery of barrier structure and function.
Journal of Lipid Research, 1989 Previous studies have demonstrated that perturbations in barrier function stimulate epidermal lipid synthesis and that this increase can be prevented by occlusive membranes.
G Grubauer, P M Elias, K R Feingold
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