Results 31 to 40 of about 92,135 (253)
Epidermal Hyaluronan in Barrier Alteration-Related Disease
Cells, 2021 In skin, although the extracellular matrix (ECM) is highly developed in dermis and hypodermis, discrete intercellular spaces between cells of the living epidermal layers are also filled with ECM components.
Céline Evrard +2 more
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The “Caveolae Brake Hypothesis” and the Epidermal Barrier [PDF]
Journal of Investigative Dermatology, 2009 Epidermal permeability barrier formation depends upon lamellar body (LB) secretion/fusion with the apical plasma membrane (APM) of outermost stratum granulosum (SG) cell, creating cholesterol/glycosphingolipid-enriched lipid rafts-like domains. We found that the dimensions of these domains are comparable to lipid raft in other cell types; and that ...
Roelandt, Truus +12 more
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Xerosis: a Dysfunction of the Epidermal Barrier
Actas Dermo-Sifiliográficas (English Edition), 2008 Xerosis or dry skin is a common skin disorder among the general population. It is characterized clinically by rough, scaly, and often itchy skin. This disorder is present in the course of some dermatoses such as atopic dermatitis, although it can also occur in healthy individuals if a combination of certain etiologic factors is present.
D, Barco, A, Giménez-Arnau
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Psoriasis as a barrier disease
Dermatologica Sinica, 2015 Skin is equipped with a barrier function, in particular, to prevent invasion of pathogens. Skin barrier is composed of a mechanical barrier, a permeability barrier, and innate and adaptive immunity barriers.
Shigetoshi Sano
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Relationship of epidermal lipogenesis to cutaneous barrier function.
Journal of Lipid Research, 1987 Although the lipids of mammalian stratum corneum are known to be important for the cutaneous permeability barrier, the factors that regulate epidermal lipid biosynthesis are poorly understood.
G Grubauer, K R Feingold, P M Elias
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Cytokine regulation of the epidermal barrier
Clinical & Experimental Allergy, 2013 Summary Studies published in recent years have highlighted the role of epidermal barrier defects in both atopic skin disease and the development of broader allergic manifestations. While genetic determinants of barrier function are important, it is clear that local acquired effects are also involved in disease pathogenesis.
Gutowska-Owsiak, D, Ogg, G
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De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements.
Journal of Lipid Research, 1985 Recent studies suggest: that the epidermis and pilosebaceous epithelium are important sites of de novo sterol synthesis, and that the rate of cutaneous cholesterol synthesis does not change with alterations in circulating sterol levels.
G K Menon +4 more
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The Journal of Clinical Investigation, 2022 Human β-defensin-3 (hBD-3) exhibits antimicrobial and immunomodulatory activities; however, its contribution to autophagy regulation remains unclear, and the role of autophagy in the regulation of the epidermal barrier in atopic dermatitis (AD) is poorly
Ge Peng +18 more
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Benefits of topical natural ingredients in epidermal permeability barrier
Frontiers in PhysiologyBecause of the crucial role of epidermal permeability barrier in regulation of cutaneous and extracutaneous functions, great efforts have been made to identify and develop the regimens that can improve epidermal permeability barrier function.
Dongyun Lei +5 more
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Regulation of epidermal sphingolipid synthesis by permeability barrier function.
Journal of Lipid Research, 1991 A mixture of sphingolipids, cholesterol, and free fatty acids forms the intercellular membrane bilayers of the stratum corneum which are presumed to regulate epidermal barrier function.
WM Holleran +5 more
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