Results 41 to 50 of about 92,135 (253)
An optimized inexpensive emollient mixture improves barrier repair in murine skin
Dermatologica Sinica, 2015 Background/Objective: Maintenance of epidermal permeability barrier homeostasis is the most crucial cutaneous function, as it allows life in a terrestrial environment. Defective epidermal permeability barrier results not only in excessive water loss, but
George Man +6 more
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Scientific Reports, 2021 Psoriasis affects more than 125 million people worldwide, and the diagnosis and treatment efficacy evaluation of the disease mainly rely on clinical assessments that could be subjective.
Chao-Chun Yang +7 more
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Ontogeny of the Epidermal Permeability Barrier
Journal of Investigative Dermatology Symposium Proceedings, 1998 A competent permeability barrier must be present by the end of gestation to allow for life in a terrestrial environment. Indeed, early preterm infants display serious complications of skin immaturity. Yet, regardless of their degree of prematurity, all infants quickly develop a competent barrier.
Williams, Mary L. +3 more
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Вестник Витебского государственного медицинского университета, 2022 The review continues the series of planned articles on the morphoneuroimmunoendocrine system of the skin (MNIESS). In this review the origin, structure and functions of epidermal cells: keratinocytes, dendritic Langerhans cells, dendritic gamma/delta T ...
M.A. Miadzelets +2 more
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Stem Cell Reports, 2014 Cornification and epidermal barrier defects are associated with a number of clinically diverse skin disorders. However, a suitable in vitro model for studying normal barrier function and barrier defects is still lacking.
Anastasia Petrova +16 more
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Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice. [PDF]
PLoS ONE, 2012 Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal ...
Zhixing Wang +8 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis
Molecular Metabolism, 2021 Objectives: The skin is the largest sensory organ of the human body and plays a fundamental role in regulating body temperature. However, adaptive alterations in skin functions and morphology have only vaguely been associated with physiological responses
Ditte Neess +14 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Current Issues in Molecular BiologySkin barrier dysfunction and thin epidermis are hallmarks of sensitive skin and contribute to premature aging. Avenanthramides are the primary bioactive components of colloidal oatmeal, a commonly used treatment to enhance skin barrier function.
Jiye Park +5 more
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