Skin evaluation of turmeric/epigallocatechin-3-gallate emulgel for skin irritation and sensitisation effects in healthy Thai participants (TULIP): a protocol for a randomised, double-blind, placebo-controlled trial. [PDF]
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Purpose The purpose of the study was to explore the possibility of utilization of epigallocatechin-3-gallate (EGCG) as a novel preservative in cheese. EGCG has strong antioxidant and antimicrobial properties and may be commercially exploited as a natural antioxidant and preservative in cheese like products which are highly susceptible to lipid ...
Deepak Mahajan, Z.F. Bhat, Sunil Kumar
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Antioxidant Nanocomplexes for Delivery of Epigallocatechin-3-gallate
Journal of Agricultural and Food Chemistry, 2016Modification of chitosan (CS) through grafting with caffeic acid (CA, CA-g-CS) and ferulic acid (FA, FA-g-CS) significantly improved its solubility under neutral and alkaline environments. Spherical and physicochemically stable nanocomplexes assembled from the phenolic acid grafting CS and caseinophosphopeptide (CPP) were obtained with particle size
Bing, Hu +6 more
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Microneedle‐mediated intradermal delivery of epigallocatechin‐3‐gallate
International Journal of Cosmetic Science, 2016AbstractObjectiveEpigallocatechin‐3‐gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50–80% of green tea catechins. It is an anti‐inflammatory, antioxidant, chemopreventive and skin photoprotective agent. However, light sensitivity and low permeability of EGCG across the stratum corneum due to its high molecular ...
A, Puri, H X, Nguyen, A K, Banga
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Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate
Drug and Chemical Toxicology, 2022Methotrexate (MTX) is currently used as first-line therapy for autoimmune diseases like rheumatoid arthritis, psoriasis, and systemic lupus erythematous. However, its use is limited by its hepatotoxic potential. Epigallocatechin-3-gallate (EGCG), an abundant catechin present in tea possesses potent antioxidant activity and effectively ameliorates ...
Ayan Pradhan +3 more
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Promotion of Neuronal Plasticity by (−)-Epigallocatechin-3-Gallate
Neurochemical Research, 2007The consumption of (-)-epigallocatechin-3-gallate (EGCG), the major polyphenolic compound found in green tea, has been associated with various neurological benefits including cognitive improvement. The physiological basis for this effect is unknown. In this study, we used synaptic transmission between the CA3 and CA1 regions (Schaffer collateral) of ...
Wen, Xie +3 more
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(−)-Epigallocatechin-3-gallate Inhibits Fibrillogenesis of Chicken Cystatin
Journal of Agricultural and Food Chemistry, 2015Previous studies have reported that (-)-epigallocatechin-3-gallate (EGCG), the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. To elucidate whether this antifibril activity is specific to disease-related target proteins or is more generic, we investigated the ability of EGCG to ...
Na, Wang +13 more
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Topical epigallocatechin‐3‐gallate in the treatment of vitiligo
Australasian Journal of Dermatology, 2021AbstractObjectiveTo preliminarily assess the efficacy and safety of the topical application of Epigallocatechin‐3‐gallate (EGCG) in treating vitiligo, a 6‐month clinical trial was carried out.MethodPatients were randomly given topical application of EGCG on the assigned lesions, with pimecrolimus being used as the control for twice a day over a 6‐month
Wenting Hu +5 more
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Epigallocatechin 3-gallate: From green tea to cancer therapeutics
Food Chemistry, 2022Epigallocatechin 3-gallate (EGCG) possesses various biological functions, including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic component originating from green tea extract that has exhibited versatile bioactivities in combating several cancers.
Manzar, Alam +5 more
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Proposed mechanisms of (−)-epigallocatechin-3-gallate for anti-obesity
Chemico-Biological Interactions, 2007Green tea catechins (GTCs) are polyphenolic flavonoids formerly called vitamin P. GTCs, especially (-)-epigallocatechin-3-gallate (EGCG), lower the incidence of cancers, collagen-induced arthritis, oxidative stress-induced neurodegenerative diseases, and streptozotocin-induced diabetes.
Hyun-Seuk, Moon +4 more
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